Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CKS1B | P61024 | 9/20 | 0.45 |
| ▸ | SKP2 | Q13309 | 9/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | METAP2 | P50579 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7851079 | 0.86 | PDE10A (0.50) | ALDH1A1CKS1BSKP2RAB9ANPC1 | |
| SCHEMBL7841610 | 0.84 | RAB9A (0.48) | ALDH1A1CKS1BSKP2RAB9ANPC1 | |
| SCHEMBL8825992 | 0.80 | ALDH1A1 (0.45) | ALDH1A1CKS1BSKP2RAB9ANPC1 | |
| SCHEMBL7849985 | 0.74 | PDE10A (0.48) | ALDH1A1CKS1BSKP2RAB9ANPC1 | |
| SCHEMBL8138083 | 0.71 | PDE10A (0.52) | ALDH1A1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL7851305 | 0.71 | ALDH1A1 (0.57) | ALDH1A1CKS1BSKP2RAB9ANPC1 | |
| SCHEMBL7849961 | 0.71 | ALDH1A1 (0.51) | ALDH1A1CKS1BSKP2RAB9ANPC1 | |
| SCHEMBL19761033 | 0.70 | NQO2 (0.37) | ALDH1A1RAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL7841723 | 0.70 | ALDH1A1 (0.62) | ALDH1A1CKS1BSKP2RAB9ANPC1 | |
| SCHEMBL9642141 | 0.70 | ALDH1A1 (0.50) | ALDH1A1CKS1BSKP2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717743-B1 | N-ARYL 1,2,4]TRIAZOLO 1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES | DOW AGROSCIENCES LLC (US) | 2001-11-14 | — | — | EP | disclosed |
| EP-0972774-A2 | 2-Benzylthio-8-amino(1,2,4)triazolo(1,5-pyridines | Dow AgroSciences LLC (US) | 2000-01-19 | — | — | EP | disclosed |
| EP-0789698-B1 | N-(1-ETHYL-4-PYRAZOLYL)TRIAZOLOAZINESULFONAMIDE HERBICIDES | DOW AGROSCIENCES LLC (US) | 1999-07-07 | — | — | EP | disclosed |
| US-5571775-A | EFFECTIVE ON A BROAD SPECTRUM OF VEGETATION AT LOW APPLICATION RATES | DOWELANCO (US) | 1996-11-05 | — | — | US | disclosed |
| EP-0717743-A1 | N-ARYL 1,2,4]TRIAZOLO 1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES | DOWELANCO (US) | 1996-06-26 | — | — | EP | disclosed |
| WO-1996001826-A1 | N-ARYL[1,2,4]TRIAZOLO[1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES | DOWELANCO (US) | 1996-01-25 | — | — | WO | disclosed |