Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 8/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | METAP2 | P50579 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 3/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7842366 | 0.80 | ALDH1A1 (0.46) | ALDH1A1RAB9ANPC1METAP2KMT2A | |
| SCHEMBL7851079 | 0.75 | PDE10A (0.50) | ALDH1A1RAB9ANPC1METAP2KMT2A | |
| SCHEMBL9641813 | 0.75 | ALDH1A1 (0.49) | ALDH1A1RAB9ANPC1METAP2KMT2A | |
| SCHEMBL7841610 | 0.74 | RAB9A (0.48) | ALDH1A1RAB9ANPC1METAP2KMT2A | |
| SCHEMBL9833711 | 0.74 | RAB9A (0.56) | ALDH1A1RAB9ANPC1METAP2KMT2A | |
| SCHEMBL9534369 | 0.74 | ALDH1A1 (0.48) | ALDH1A1RAB9ANPC1METAP2KMT2A | |
| SCHEMBL7851305 | 0.72 | ALDH1A1 (0.57) | ALDH1A1RAB9ANPC1METAP2KMT2A | |
| SCHEMBL9831659 | 0.71 | RAB9A (0.60) | ALDH1A1RAB9ANPC1METAP2KMT2A | |
| SCHEMBL9539074 | 0.71 | ALDH1A1 (0.53) | ALDH1A1RAB9ANPC1METAP2KMT2A | |
| SCHEMBL9640970 | 0.70 | ALDH1A1 (0.49) | ALDH1A1RAB9ANPC1METAP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602075-A | N-aryl[1,2,4]triazolo[1,5-a]pyrazine-2-sulfonamide herbicides | DOWELANCO (US) | 1997-02-11 | — | — | US | disclosed |