Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6087870 | 0.92 | SMN1; SMN2 (0.38) | ALDH1A1HPGDHSD17B10SMN1; SMN2KMT2A | |
| SCHEMBL7850057 | 0.83 | GRIN1 (0.37) | ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7850932 | 0.82 | ALDH1A1 (0.34) | ALDH1A1HPGDHSD17B10SMN1; SMN2KMT2A | |
| SCHEMBL7855069 | 0.82 | TYMP (0.31) | — | |
| SCHEMBL7854164 | 0.81 | GRIN1 (0.34) | KMT2A | |
| SCHEMBL501343 | 0.80 | PDE3B (0.38) | ALDH1A1SMN1; SMN2LMNAMAPK1TSHR | |
| SCHEMBL1484872 | 0.80 | ALDH1A1 (0.34) | ALDH1A1HPGDHSD17B10LMNATP53 | |
| SCHEMBL1484869 | 0.80 | ALDH1A1 (0.34) | ALDH1A1HPGDHSD17B10LMNATP53 | |
| SCHEMBL7757632 | 0.80 | ALDH1A1 (0.34) | ALDH1A1HPGDHSD17B10LMNATP53 | |
| SCHEMBL7848465 | 0.79 | ROCK2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |