Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | PDE9A | O76083 | 1/20 | 0.31 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086491 | 0.92 | PDE5A (0.33) | PDE5APDE9APDE1APDE1BPDE1C | |
| SCHEMBL6087128 | 0.85 | TPH1 (0.34) | — | |
| SCHEMBL7852868 | 0.82 | PIK3R1 (0.39) | — | |
| SCHEMBL7851564 | 0.82 | TYMP (0.32) | TYMP | |
| SCHEMBL6087770 | 0.82 | TYMS (0.37) | — | |
| SCHEMBL7848465 | 0.82 | ROCK2 (0.32) | — | |
| SCHEMBL6086817 | 0.82 | HPGD (0.43) | — | |
| SCHEMBL7842674 | 0.82 | ALDH1A1 (0.33) | — | |
| SCHEMBL7850057 | 0.81 | GRIN1 (0.37) | — | |
| SCHEMBL7850946 | 0.80 | NPBWR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |