SCHEMBL7842815

SCHEMBL7842815

C#CCCC(=O)NCCO.CCN(CC)CCN1C(=O)C(O)(c2ccc3ccccc3c2)c2c1cc(C#CCCC(=O)NCCO)cc2C(F)(F)F

nearest known ligand 0.75

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 16/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6177362 0.97 GHSR (0.80) GHSR
SCHEMBL6178796 0.87 GHSR (0.86) GHSR
SCHEMBL6181326 0.86 GHSR (0.85) GHSR
SCHEMBL6178939 0.86 GHSR (0.80) GHSR
SCHEMBL6176019 0.86 GHSR (0.62) GHSR
SCHEMBL6179365 0.86 GHSR (0.89) GHSR
SCHEMBL6180361 0.84 GHSR (0.81) GHSR
SCHEMBL6180416 0.83 GHSR (0.82) GHSR
SCHEMBL6178202 0.83 GHSR (0.75) GHSR
SCHEMBL6177831 0.83 GHSR (0.78) GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1105376-A1 OXINDOLE DERIVATIVES AS GROWTH HORMONE RELEASERS SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2001-06-13 EP disclosed
WO-2000010975-A1 OXINDOLE DERIVATIVES AS GROWTH HORMONE RELEASERS SUMITOMO PHARMACEUTICALS CO., LTD. (JP) 2000-03-02 WO disclosed