Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 5/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.40 |
| ▸ | TYMP | P19971 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305559 | 0.88 | BRS3 (0.50) | BRS3HRH3MMP12MMP13SAE1 | |
| Hydrochloric Acid SCHEMBL8368581 | 0.87 | BRS3 (0.52) | BRS3HRH3MMP12MMP13SAE1 | |
| SCHEMBL7129739 | 0.83 | BRS3 (0.52) | BRS3HRH3SAE1UBA2TYMP | |
| SCHEMBL7345076 | 0.83 | BRS3 (0.49) | BRS3DAOMMP2 | |
| SCHEMBL7839484 | 0.81 | BRS3 (0.50) | BRS3HRH3MMP12MMP13SAE1 | |
| SCHEMBL8498703 | 0.80 | BRS3 (0.49) | BRS3HRH3SAE1UBA2TYMP | |
| SCHEMBL7505077 | 0.80 | LOXL2 (0.49) | BRS3HRH3SAE1UBA2TYMP | |
| SCHEMBL10588302 | 0.80 | BRS3 (0.49) | BRS3HRH3SAE1UBA2TYMP | |
| SCHEMBL7468902 | 0.80 | HRH3 (0.48) | BRS3HRH3SAE1UBA2TYMP | |
| SCHEMBL7468183 | 0.80 | BRS3 (0.47) | BRS3HRH3SAE1UBA2TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140942-A2 | PRENYL TRANSFERASE INHIBITORS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039130-A2 | PRENYL TRANSFERASE INHIBITORS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) | 2000-07-06 | — | — | WO | disclosed |