Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7850370 | 0.83 | L3MBTL1 (0.47) | ALDH1A1MAPTTDP1HTTMAPK1 | |
| SCHEMBL1921859 | 0.81 | BRD4 (0.42) | ALDH1A1MAPTBRD4HTTCA12 | |
| SCHEMBL7853990 | 0.79 | L3MBTL1 (0.44) | ALDH1A1MAPTNPC1RAB9AHPGD | |
| SCHEMBL19017656 | 0.78 | CYP2C19 (0.47) | ALDH1A1MAPTTDP1SMN1; SMN2LMNA | |
| SCHEMBL7851483 | 0.77 | MAPT (0.40) | ALDH1A1MAPTCA12CA1CA2 | |
| SCHEMBL7851482 | 0.75 | COMT (0.43) | ALDH1A1MAPTTDP1NPC1RAB9A | |
| SCHEMBL30038114 | 0.75 | HTT (0.50) | ALDH1A1MAPTHTTMAPK1KDM4E | |
| SCHEMBL14679109 | 0.74 | CA12 (0.51) | ALDH1A1MAPTTDP1CA12CA1 | |
| SCHEMBL7852266 | 0.74 | COMT (0.41) | ALDH1A1TDP1NPC1RAB9AHPGD | |
| SCHEMBL8785261 | 0.74 | LMNA (0.46) | MAPTCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0652218-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-07-11 | — | — | EP | disclosed |
| US-5585385-A | USEFUL IN TREATING DISORDERS OF MICTURITION; ADMINISTERING TO INHIBIT PLASMA EXTRAVASATION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-17 | — | — | US | disclosed |