Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7853990 | 0.94 | L3MBTL1 (0.44) | L3MBTL1RAB9ATSHRCASP3SENP8 | |
| SCHEMBL7843213 | 0.83 | ALDH1A1 (0.39) | RAB9AALDH1A1MAPTHPGDHTT | |
| SCHEMBL12547281 | 0.71 | KMT2A (0.51) | L3MBTL1RAB9ATSHRALDH1A1MAPT | |
| SCHEMBL14398958 | 0.71 | HTT (0.59) | L3MBTL1RAB9ATSHRPOLBALDH1A1 | |
| SCHEMBL187899 | 0.70 | ALDH1A1 (0.55) | L3MBTL1RAB9ATSHRALDH1A1NPSR1 | |
| SCHEMBL7515538 | 0.70 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1MAPTHPGDHTT | |
| SCHEMBL7851482 | 0.70 | COMT (0.43) | L3MBTL1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL7852266 | 0.70 | COMT (0.41) | RAB9ACASP3SENP8SENP7SENP6 | |
| SCHEMBL21814404 | 0.70 | ALDH1A1 (0.54) | L3MBTL1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL31515547 | 0.69 | ALDH1A1 (0.50) | L3MBTL1TSHRALDH1A1NPSR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0652218-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-07-11 | — | — | EP | disclosed |
| US-5585385-A | USEFUL IN TREATING DISORDERS OF MICTURITION; ADMINISTERING TO INHIBIT PLASMA EXTRAVASATION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-17 | — | — | US | disclosed |
| EP-0652218-A1 | Heterocyclic compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1995-05-10 | — | — | EP | disclosed |