Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2940872 | 0.81 | ALDH1A1 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31464162 | 0.79 | DAO (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3659417 | 0.77 | DAO (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6030268 | 0.77 | CA12 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5737532 | 0.76 | CA12 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8628954 | 0.76 | DAO (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5025168 | 0.76 | LMNA (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL938203 | 0.76 | CA12 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3388651 | 0.75 | CA12 (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5856765 | 0.75 | CA12 (0.49) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934295-B1 | NOVEL BI-AROMATIC DIBENZOFURAN DERIVATIVES AND THEIR USE IN HUMAN AND VETERINARY MEDICINE AND IN COSMETICS | CT INTERNAT DE (FR) | 2001-03-07 | — | — | EP | disclosed |
| US-6057341-A | USE IN PHARMACEUTICAL COMPOSITIONS FOR HUMAN OR VETERINARY MEDICINE (SKIN, RHEUMATIC RESPIRATORY, CARDIOVASCULAR, AND OPHTHALMOLOGIC DISORDERS), OR IN COSMETIC COMPOSITIONS AS WELL | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 2000-05-02 | — | — | US | disclosed |
| EP-0709382-B1 | Aromatic dibenzofurane derivatives, pharmaceutical and cosmetic compositions containing them | CIRD GALDERMA (FR) | 1999-11-10 | — | — | EP | disclosed |
| US-5840917-A | ADMINISTERING TO MAMMAL TO ERADICATE HELICOBACTER PYLORI | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-24 | — | — | US | disclosed |
| WO-1998042347-A1 | PHARMACEUTICAL COMPOSITION CONTAINING A PHOSPHORYLAMIDE AND AN AYNTIBIOTIC | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-01 | — | — | WO | disclosed |
| EP-0852498-A1 | PHOSPHORYLAMIDES, THEIR PREPARATION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1998-07-15 | — | — | EP | disclosed |
| US-5747530-A | Aromatic dibenzofuran compounds and pharmaceutical/cosmetic compositions comprised thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-05-05 | — | — | US | disclosed |
| WO-1997011705-A1 | PHOSPHORYLAMIDES, THEIR PREPARATION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-04-03 | — | — | WO | disclosed |
| EP-0709382-A1 | Aromatic dibenzofurane derivatives, pharmaceutical and cosmetic compositions containing them | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) | 1996-05-01 | — | — | EP | disclosed |
| US-5498755-A | IMINE COMPOUNDS FOR SKIN DISORDERS AND ANTIINFLAMMATORY AGENTS | ALLERGAN, INC. | 1996-03-12 | — | — | US | disclosed |
| WO-1996006070-A1 | DISUBSTITUTED ARYL AND HETEROARYL IMINES HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY | ALLERGAN (US) | 1996-02-29 | — | — | WO | disclosed |