Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 5/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | RHEB | Q15382 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22711467 | 0.73 | CCR5 (0.51) | MEN1ALDH1A1KMT2ASMN1; SMN2MAOB | |
| SCHEMBL30587785 | 0.72 | HTR2A (0.50) | KDM4EMEN1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL23817083 | 0.72 | CYP1A2 (0.53) | KDM4EMEN1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL30394966 | 0.72 | CYP1A2 (0.53) | KDM4EMEN1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL4700070 | 0.72 | HTR2A (0.50) | KDM4EMEN1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL6614179 | 0.72 | MAOA (0.58) | KDM4EMEN1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL20155306 | 0.70 | MAOA (0.57) | KDM4EMEN1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL16891287 | 0.69 | HTR2A (0.47) | KDM4EMEN1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL7618895 | 0.69 | MAPT (0.41) | MEN1ALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL9272342 | 0.69 | MAPT (0.50) | KDM4EMEN1ALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090009-A2 | CELL ADHESION-INHIBITING ANTINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999062908-A2 | CELL ADHESION-INHIBITING ANTINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 1999-12-09 | — | — | WO | disclosed |