SCHEMBL30587785

SCHEMBL30587785

Clc1ccc(Oc2ccccc2Br)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 3/20 0.50
SLC6A4 P31645 3/20 0.50
HTT P42858 3/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A3 Q01959 1/20 0.50
PNLIP P16233 1/20 0.47
KMT2A Q03164 4/20 0.44
MAPT P10636 3/20 0.44
ALDH1A1 P00352 3/20 0.44
MEN1 O00255 3/20 0.44
HPGD P15428 3/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
KDM4E B2RXH2 1/20 0.44
CYP2D6 P10635 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
MAPK1 P28482 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
MAOA P21397 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4700070 1.00 HTR2A (0.50) HTR2ASLC6A4HTTSLC6A2SLC6A3
SCHEMBL74839 0.89 ALDH1A1 (0.52) SLC6A4HTTSLC6A2SLC6A3KMT2A
SCHEMBL3843172 0.87 ALDH1A1 (0.50) SLC6A4HTTSLC6A2SLC6A3KMT2A
SCHEMBL8954758 0.83 LTA4H (0.55) SLC6A4HTTSLC6A2KMT2AALDH1A1
SCHEMBL3845666 0.83 SLC6A4 (0.53) SLC6A4HTTSLC6A2SLC6A3KMT2A
SCHEMBL130304 0.82 LTA4H (0.52) SLC6A4HTTSLC6A2SLC6A3KMT2A
SCHEMBL3898531 0.81 ALDH1A1 (0.49) SLC6A4HTTSLC6A2SLC6A3KMT2A
SCHEMBL30039490 0.81 ALDH1A1 (0.49) SLC6A4HTTSLC6A2SLC6A3KMT2A
SCHEMBL16891287 0.81 HTR2A (0.47) HTR2ASLC6A4HTTSLC6A2SLC6A3
SCHEMBL4859489 0.80 LTA4H (0.50) SLC6A4HTTSLC6A2SLC6A3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116925090-A Spiro compound and application thereof in organic light-emitting device and panel 上海天马微电子有限公司 2023-10-24 CN disclosed