Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31358642 | 1.00 | SLC22A12 (0.42) | SLC22A12PTGES2DRD1TRPV4ELANE | |
| SCHEMBL11094970 | 0.81 | HTR6 (0.35) | PTGES2ELANEKMT2ACA1CA2 | |
| SCHEMBL11070176 | 0.80 | MEN1 (0.36) | DRD1KMT2AHTTSMN1; SMN2POLB | |
| SCHEMBL10962213 | 0.80 | TSHR (0.36) | SLC22A12PTGES2ELANEKMT2AHTT | |
| SCHEMBL10719372 | 0.79 | SMN1; SMN2 (0.32) | SLC22A12DRD1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL9871995 | 0.78 | HTR6 (0.51) | SLC22A12KMT2ASMN1; SMN2CA1CA2 | |
| SCHEMBL38652743 | 0.78 | HTR6 (0.51) | SLC22A12KMT2ASMN1; SMN2CA1CA2 | |
| SCHEMBL9523901 | 0.77 | DRD1 (0.40) | DRD1ELANEHTR6 | |
| SCHEMBL6227949 | 0.77 | SLC22A12 (0.43) | SLC22A12PTGES2ELANEHTR6 | |
| SCHEMBL31358651 | 0.77 | SLC22A12 (0.43) | SLC22A12PTGES2ELANEHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064322-B1 | BENZENESULFONYL ISOCYANATES, ISOTHIOCYANATES, CHLORIDES, AND SULFONAMIDES HAVING A FLUORINATED SUBSTITUENT | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-05-22 | — | — | EP | claimed |
| EP-0064322-A2 | Benzenesulfonyl isocyanates, isothiocyanates, chlorides, and sulfonamides having a fluorinated substituent | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-11-10 | — | — | EP | claimed |
| EP-1082312-A1 | SULFONYL AMINO (THIO)CARBONYL TRIAZOLINE (THI)ONS HAVING ALKENYL SUBSTITUENTS | Bayer Aktiengesellschaft (DE) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999061429-A1 | SULFONYL AMINO (THIO)CARBONYL TRIAZOLINE (THI)ONS HAVING ALKENYL SUBSTITUENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-12-02 | — | — | WO | disclosed |
| US-4996208-A | Pesticidal thiazolopyrimidine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-26 | — | — | US | disclosed |
| US-4944792-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1990-07-31 | — | — | US | disclosed |
| US-4944794-A | N-phenylsulfonyl-N-triazinylureas | CIBA-GEIGY CORPORATION (US) | 1990-07-31 | — | — | US | disclosed |
| EP-0348746-A2 | Thiazolopyrimidine derivatives, process for their preparation and their use as pest control agents | BAYER AG (DE) | 1990-01-03 | — | — | EP | disclosed |
| EP-0108708-B1 | N-(CYCLOPROPYL-TRIAZINYL- AND -PYRIMIDINYL)-N'-(ARYLSULFONYL) UREAS WITH HERBICIDAL ACTIVITY | CIBA-GEIGY AG (CH) | 1989-06-14 | — | — | EP | disclosed |
| US-4693741-A | HERBICIDES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1987-09-15 | — | — | US | disclosed |
| EP-0070804-B1 | FLUORALKOXY-AMINOPYRIMIDINES AND DITTO TRIAZINES | CIBA-GEIGY AG (CH) | 1987-04-08 | — | — | EP | disclosed |
| US-4515626-A | PLANT GROWTH REGULATORS | CIBA GEIGY CORPORATION (US) | 1985-05-07 | — | — | US | disclosed |
| US-4480101-A | HERBICIDE INTERMEDIATES | CIBA-GEIGY CORPORATION (US) | 1984-10-30 | — | — | US | disclosed |
| US-4476321-A | HERBICIDES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1984-10-09 | — | — | US | disclosed |
| EP-0108708-A2 | N-(cyclopropyl-triazinyl- and -pyrimidinyl)-N'-(arylsulfonyl) ureas with herbicidal activity | CIBA-GEIGY AG (CH) | 1984-05-16 | — | — | EP | disclosed |
| EP-0082108-A1 | N-phenylsulfonyl-N'-pyrimidinyl and triazinyl urea | CIBA-GEIGY AG (CH) | 1983-06-22 | — | — | EP | disclosed |
| EP-0072347-A1 | N-phenylsulfonyl-N'-pyrimidinyl and -triazinyl ureas | CIBA-GEIGY AG (CH) | 1983-02-16 | — | — | EP | disclosed |
| EP-0070804-A2 | Fluoralkoxy-aminopyrimidines and ditto triazines | CIBA-GEIGY AG (CH) | 1983-01-26 | — | — | EP | disclosed |
| EP-0064322-A2 | Benzenesulfonyl isocyanates, isothiocyanates, chlorides, and sulfonamides having a fluorinated substituent | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-11-10 | — | — | EP | disclosed |
| EP-0044808-A2 | N-phenylsulfonyl-N'-pyrimidinyl- and -triazinyl ureas | CIBA-GEIGY AG (CH) | 1982-01-27 | — | — | EP | disclosed |