Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 9/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38652743 | 1.00 | HTR6 (0.51) | HTR6KMT2APKMCA12CA1 | |
| SCHEMBL10863861 | 0.90 | HTR6 (0.42) | HTR6KMT2APKMCA12CA1 | |
| SCHEMBL38652887 | 0.87 | CA2 (0.43) | HTR6KMT2ACA12CA1CA2 | |
| SCHEMBL7806811 | 0.83 | ELANE (0.40) | HTR6KMT2ASMN1; SMN2 | |
| SCHEMBL11094970 | 0.82 | HTR6 (0.35) | HTR6KMT2APKMCA1CA2 | |
| SCHEMBL38661865 | 0.81 | ALDH1A1 (0.41) | CA12CA1CA2CA9CA14 | |
| SCHEMBL10735199 | 0.81 | ALDH1A1 (0.41) | CA12CA1CA2CA9CA14 | |
| SCHEMBL11092403 | 0.81 | AR (0.36) | HTR6CA2ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL6585748 | 0.81 | HTR6 (0.58) | HTR6KMT2APKMCA12CA1 | |
| SCHEMBL6677573 | 0.80 | GAA (0.36) | HTR6KMT2ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4954628-A | HERBICIDES, PLANT GROWTH REGULATORS, PHARMACEUTICALS | NITROKAELEPEK (HU) | 1990-09-04 | — | — | US | claimed |
| CN-1171197-A | Method for synthesizing herbicide of sulfonylureas | ZHANG HUIMING (CN) | 1998-01-28 | — | — | CN | disclosed |
| US-4996208-A | Pesticidal thiazolopyrimidine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-26 | — | — | US | disclosed |
| US-4954628-A | HERBICIDES, PLANT GROWTH REGULATORS, PHARMACEUTICALS | NITROKAELEPEK (HU) | 1990-09-04 | — | — | US | disclosed |
| EP-0348746-A2 | Thiazolopyrimidine derivatives, process for their preparation and their use as pest control agents | BAYER AG (DE) | 1990-01-03 | — | — | EP | disclosed |