Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 8/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38661865 | 0.84 | ALDH1A1 (0.41) | — | |
| SCHEMBL10735199 | 0.84 | ALDH1A1 (0.41) | — | |
| SCHEMBL10964603 | 0.83 | ADRA1D (0.36) | DRD2ELANE | |
| SCHEMBL10750781 | 0.83 | ALOX5AP (0.35) | ELANE | |
| SCHEMBL11073000 | 0.81 | MAPT (0.44) | DRD2 | |
| SCHEMBL8744518 | 0.81 | ALDH1A1 (0.32) | ELANE | |
| SCHEMBL10731858 | 0.81 | MEN1 (0.38) | — | |
| SCHEMBL27535971 | 0.81 | ELANE (0.31) | ELANE | |
| SCHEMBL11092403 | 0.80 | AR (0.36) | HTR6 | |
| SCHEMBL11156526 | 0.79 | RIPK1 (0.44) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251079-B1 | 3-SUBSTITUTED 1-(2-HALOGENOALKOXY-BENZENSULFONYL)-3-HETEROARYLUREA | BAYER AG (DE) | 1993-05-19 | — | — | EP | claimed |
| EP-0251079-B1 | 3-SUBSTITUTED 1-(2-HALOGENOALKOXY-BENZENSULFONYL)-3-HETEROARYLUREA | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |