Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 2/20 | 0.54 |
| ▸ | PRKACG | P22612 | 2/20 | 0.54 |
| ▸ | PRKACB | P22694 | 2/20 | 0.54 |
| ▸ | PRKCB | P05771 | 3/20 | 0.52 |
| ▸ | PRKCG | P05129 | 2/20 | 0.52 |
| ▸ | PRKCA | P17252 | 2/20 | 0.52 |
| ▸ | PRKCH | P24723 | 2/20 | 0.52 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.52 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.52 |
| ▸ | HTR6 | P50406 | 4/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | CAMK2D | Q13557 | 3/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7843953 | 0.88 | PRKCB (0.52) | PRKACAPRKACGPRKACBPRKCBPRKCG | |
| SCHEMBL7832859 | 0.83 | HTR6 (0.46) | PRKACAPRKACGPRKACBPRKCBPRKCG | |
| SCHEMBL7842723 | 0.77 | HTR6 (0.49) | HTR6BCHEFEN1KDM1AACKR3 | |
| SCHEMBL23871348 | 0.72 | ACKR3 (0.51) | HTR6BCHEFEN1KDM1AACKR3 | |
| SCHEMBL21605864 | 0.72 | ACKR3 (0.51) | HTR6BCHEFEN1KDM1AACKR3 | |
| SCHEMBL29244762 | 0.72 | ACKR3 (0.51) | HTR6BCHEFEN1KDM1AACKR3 | |
| SCHEMBL13047247 | 0.71 | FEN1 (0.47) | HTR6BCHEFEN1KDM1AACKR3 | |
| SCHEMBL2997356 | 0.71 | FEN1 (0.47) | HTR6BCHEFEN1KDM1AACKR3 | |
| SCHEMBL13047240 | 0.71 | FEN1 (0.47) | HTR6BCHEFEN1KDM1AACKR3 | |
| SCHEMBL31302652 | 0.71 | EPHX1 (0.54) | HTR6BCHEFEN1KDM1AACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1120414-A1 | DISUBSTITUTED MALEIMIDE COMPOUNDS AND MEDICINAL UTILIZATION THEREOF | JAPAN TOBACCO INC. (JP) | 2001-08-01 | — | — | EP | disclosed |