Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCB | P05771 | 13/20 | 1.00 |
| ▸ | PRKCA | P17252 | 3/20 | 0.70 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.61 |
| ▸ | CDK4 | P11802 | 2/20 | 0.61 |
| ▸ | PRKACA | P17612 | 2/20 | 0.61 |
| ▸ | PRKACG | P22612 | 2/20 | 0.61 |
| ▸ | PRKACB | P22694 | 2/20 | 0.61 |
| ▸ | CCND1 | P24385 | 2/20 | 0.61 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.61 |
| ▸ | CDK2 | P24941 | 2/20 | 0.61 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.61 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.61 |
| ▸ | ABL1 | P00519 | 1/20 | 0.61 |
| ▸ | PRKCG | P05129 | 1/20 | 0.61 |
| ▸ | CDK1 | P06493 | 1/20 | 0.61 |
| ▸ | PIM1 | P11309 | 1/20 | 0.61 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.61 |
| ▸ | PRKCH | P24723 | 1/20 | 0.61 |
| ▸ | PRKCI | P41743 | 1/20 | 0.61 |
| ▸ | ABL2 | P42684 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7840226 | 0.84 | PRKCB (0.72) | PRKCBPRKCACCNE2CDK4PRKACA | |
| SCHEMBL7846114 | 0.84 | PRKCB (1.00) | PRKCBPRKCACCNE2CDK4PRKACA | |
| SCHEMBL31060142 | 0.83 | PRKCB (1.00) | PRKCBPRKCACCNE2CDK4PRKACA | |
| SCHEMBL7840920 | 0.83 | PRKCB (1.00) | PRKCBPRKCACCNE2CDK4PRKACA | |
| SCHEMBL7831655 | 0.81 | PRKCB (1.00) | PRKCBPRKCACCNE2CDK4PRKACA | |
| SCHEMBL13917970 | 0.80 | PRKCB (0.78) | PRKCBPRKCACCNE2CDK4PRKACA | |
| SCHEMBL7842177 | 0.79 | PRKCB (0.72) | PRKCBPRKCACCNE2CDK4PRKACA | |
| SCHEMBL7832745 | 0.78 | PRKCB (0.72) | PRKCBPRKCACDK4CCND1CDK2 | |
| Ro-316233 SCHEMBL29373011 | 0.78 | PRKCB (1.00) | PRKCBPRKCACCNE2CDK4PRKACA | |
| Ro-316233 SCHEMBL624896 | 0.78 | PRKCB (1.00) | PRKCBPRKCACCNE2CDK4PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1120414-A1 | DISUBSTITUTED MALEIMIDE COMPOUNDS AND MEDICINAL UTILIZATION THEREOF | JAPAN TOBACCO INC. (JP) | 2001-08-01 | — | — | EP | claimed |
| WO-2013029043-A1 | SELECTIVE KINASE INHIBITORS | REACTION BIOLOGY CORP. (US) | 2013-02-28 | — | — | WO | disclosed |
| EP-1120414-A1 | DISUBSTITUTED MALEIMIDE COMPOUNDS AND MEDICINAL UTILIZATION THEREOF | JAPAN TOBACCO INC. (JP) | 2001-08-01 | — | — | EP | disclosed |