Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.51 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CASP2 | P42575 | 1/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.44 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30406271 | 0.94 | SLC6A5 (0.53) | NAAASLC6A5PAOXCNR1CASP2 | |
| SCHEMBL10795093 | 0.94 | SLC6A5 (0.53) | NAAASLC6A5PAOXCNR1CASP2 | |
| SCHEMBL10953207 | 0.92 | SLC6A5 (0.59) | NAAASLC6A5PAOXCNR1CASP2 | |
| SCHEMBL17230156 | 0.92 | SLC6A5 (0.50) | NAAASLC6A5PAOXCNR1TSHR | |
| SCHEMBL16306538 | 0.90 | SLC6A5 (0.57) | NAAASLC6A5PAOXCNR1CASP2 | |
| SCHEMBL10594732 | 0.90 | SLC6A5 (0.47) | NAAASLC6A5PAOXCNR1CASP2 | |
| SCHEMBL6745342 | 0.88 | TSHR (0.54) | SLC6A5PAOXCASP2KDM4AHIF1A | |
| SCHEMBL6745339 | 0.88 | TSHR (0.54) | SLC6A5PAOXCASP2KDM4AHIF1A | |
| SCHEMBL18567204 | 0.86 | SLC6A5 (0.57) | NAAASLC6A5PAOXCNR1CASP2 | |
| SCHEMBL26415654 | 0.86 | NAAA (0.53) | NAAASLC6A5CNR1CASP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718300-B1 | Carbodiimide derivative | NISSHIN SPINNING (JP) | 2001-11-21 | — | — | EP | disclosed |
| US-5789588-A | BIOTIN DERIVATIIVES OF CARBODIIMIDE FOR NUCLEIC ACIDS AND PROTEINS | NISSHINBO INDUSTRIES, INC. (JP) | 1998-08-04 | — | — | US | disclosed |
| US-5700935-A | LABEL FOR INTRODUCING BIOTIN GROUP INTO NUCLEIC ACID | NISSHINBO INDUSTRIES, INC. (JP) | 1997-12-23 | — | — | US | disclosed |
| EP-0718300-A1 | Carbodiimide derivative | NISSHINBO INDUSTRIES, INC. (JP) | 1996-06-26 | — | — | EP | disclosed |