Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 7/20 | 0.43 |
| ▸ | HTR2A | P28223 | 6/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9377628 | 0.86 | EPHX2 (0.48) | KCNH2SLC6A2SLC6A4SLC6A3HPGD | |
| SCHEMBL205556 | 0.82 | ALDH1A1 (0.52) | SIGMAR1HTR2AALDH1A1HPGDALOX15 | |
| SCHEMBL9379664 | 0.82 | SLC6A2 (0.52) | KCNH2SIGMAR1HRH1HTR2ASLC6A2 | |
| SCHEMBL18321215 | 0.82 | KCNH2 (0.44) | KCNH2SIGMAR1HTR2AACP3SLC6A2 | |
| SCHEMBL6497060 | 0.78 | KCNH2 (0.63) | KCNH2SIGMAR1HRH1HTR2AACP3 | |
| SCHEMBL7760233 | 0.78 | HRH1 (0.50) | KCNH2SIGMAR1HRH1HTR2ASLC6A2 | |
| SCHEMBL9128295 | 0.74 | SIGMAR1 (0.38) | KCNH2SIGMAR1HTR2AACP3SLC6A2 | |
| SCHEMBL364434 | 0.74 | SIGMAR1 (0.48) | SIGMAR1HTR2ASLC6A3ADRA1AALDH1A1 | |
| SCHEMBL9132974 | 0.74 | KCNH2 (0.66) | KCNH2SIGMAR1HRH1HTR2ASLC6A2 | |
| SCHEMBL5834700 | 0.73 | GRIK1 (0.41) | KCNH2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083874-A1 | SMALL MOLECULE PIPECOLIC ACID DERIVATIVE HAIR GROWTH COMPOSITIONS AND USES | GPI NIL Holdings, Inc. (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999062491-A1 | SMALL MOLECULE PIPECOLIC ACID DERIVATIVE HAIR GROWTH COMPOSITIONS AND USES | GPI NIL HOLDINGS, INC. (US) | 1999-12-09 | — | — | WO | disclosed |