Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 7/20 | 0.50 |
| ▸ | HTR2A | P28223 | 7/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17183641 | 0.82 | AOC3 (0.39) | HRH1HTR2ASIGMAR1CYP3A4CYP1A2 | |
| SCHEMBL17183681 | 0.82 | LMNA (0.39) | HRH1HTR2ASIGMAR1CYP3A4CYP1A2 | |
| SCHEMBL7844501 | 0.78 | KCNH2 (0.52) | HRH1HTR2ASIGMAR1HTR1AADORA3 | |
| SCHEMBL17183683 | 0.77 | RIPK1 (0.46) | CYP3A4CYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL107889 | 0.77 | HRH1 (0.56) | HRH1HTR2ASIGMAR1CYP3A4CYP1A2 | |
| SCHEMBL17183749 | 0.76 | NR1I2 (0.39) | HRH1HTR2ASIGMAR1CYP3A4CYP1A2 | |
| SCHEMBL17183687 | 0.76 | RIPK1 (0.44) | SIGMAR1CYP3A4CYP1A2CYP2D6CYP2C19 | |
| Ammonia Solution, Strong SCHEMBL5724927 | 0.75 | HRH1 (0.54) | HRH1HTR2ASIGMAR1CYP3A4CYP1A2 | |
| Hydrochloric Acid SCHEMBL6521685 | 0.75 | HRH1 (0.54) | HRH1HTR2ASIGMAR1CYP3A4CYP1A2 | |
| SCHEMBL28229621 | 0.75 | HRH1 (0.54) | HRH1HTR2ASIGMAR1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083876-A1 | SMALL MOLECULE SULFONAMIDE HAIR GROWTH COMPOSITIONS AND USES | GPI NIL Holdings, Inc. (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999062490-A1 | SMALL MOLECULE SULFONAMIDE HAIR GROWTH COMPOSITIONS AND USES | GPI NIL HOLDINGS, INC. (US) | 1999-12-09 | — | — | WO | disclosed |