Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 7/20 | 0.48 |
| ▸ | HTR2A | P28223 | 7/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9377632 | 0.84 | TBXAS1 (0.51) | KCNH2SLC6A2SLC6A4SLC6A3CYP2C19 | |
| SCHEMBL9126415 | 0.84 | HRH1 (0.39) | HRH1HTR2ATAAR1CYP2D6CYP1A2 | |
| SCHEMBL3031215 | 0.83 | TAAR1 (0.43) | HRH1HTR2ATAAR1CYP3A4CYP2D6 | |
| SCHEMBL9379668 | 0.80 | SLC6A2 (0.56) | HRH1HTR2AKCNH2CYP3A4CYP2D6 | |
| SCHEMBL8394709 | 0.80 | TRPA1 (0.46) | HRH1HTR2ATAAR1CYP2D6LMNA | |
| SCHEMBL536776 | 0.80 | AOC3 (0.43) | HRH1HTR2ATAAR1OPRM1LMNA | |
| SCHEMBL7162278 | 0.80 | HRH1 (0.37) | HRH1HTR2ATAAR1CYP2D6CYP1A2 | |
| SCHEMBL3290730 | 0.80 | HRH1 (0.68) | HRH1HTR2ATAAR1KCNH2CYP3A4 | |
| SCHEMBL205557 | 0.78 | CYP19A1 (0.49) | HTR2ATAAR1KCNH2CYP3A4CYP2D6 | |
| SCHEMBL2732016 | 0.77 | HRH1 (0.65) | HRH1HTR2ATAAR1KCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083874-A1 | SMALL MOLECULE PIPECOLIC ACID DERIVATIVE HAIR GROWTH COMPOSITIONS AND USES | GPI NIL Holdings, Inc. (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999062491-A1 | SMALL MOLECULE PIPECOLIC ACID DERIVATIVE HAIR GROWTH COMPOSITIONS AND USES | GPI NIL HOLDINGS, INC. (US) | 1999-12-09 | — | — | WO | disclosed |