Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 4/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7840487 | 0.88 | CTRB1 (0.53) | CTRB1ELANEALDH1A1KMT2AGPR139 | |
| SCHEMBL6507176 | 0.87 | LMNA (0.41) | CTRB1LMNAELANEKCNK3KCNH2 | |
| SCHEMBL6504922 | 0.80 | MAPT (0.39) | CTRB1LMNAELANEENPP2ALDH1A1 | |
| SCHEMBL7839987 | 0.80 | CTRB1 (0.46) | CTRB1ELANEKMT2A | |
| SCHEMBL7813812 | 0.78 | CTRB1 (0.52) | CTRB1LMNAELANEALDH1A1KMT2A | |
| SCHEMBL6503610 | 0.75 | CTRB1 (0.49) | CTRB1ELANEALDH1A1KMT2A | |
| SCHEMBL7829580 | 0.75 | ELANE (0.43) | CTRB1ELANEALDH1A1KMT2A | |
| SCHEMBL6498129 | 0.74 | ELANE (0.44) | CTRB1ELANE | |
| SCHEMBL6498142 | 0.74 | LMNA (0.41) | CTRB1LMNAELANEALDH1A1KMT2A | |
| SCHEMBL8659635 | 0.74 | LMNA (0.39) | CTRB1LMNAELANEALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828721-B1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | SEARLE & CO (US) | 2001-11-14 | — | — | EP | claimed |