Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ESRRB | O95718 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESRRA | P11474 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4020967 | 0.77 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL10430379 | 0.77 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL29415624 | 0.72 | ALDH1A1 (0.53) | ALDH1A1ESRRBESR1ESRRAESR2 | |
| SCHEMBL258183 | 0.72 | ALDH1A1 (0.53) | ALDH1A1ESRRBESR1ESRRAESR2 | |
| SCHEMBL959915 | 0.71 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL5084622 | 0.70 | TDP1 (0.44) | ALDH1A1ESR1ESR2 | |
| SCHEMBL17628515 | 0.70 | ALDH1A1 (0.58) | ALDH1A1ESRRBESR1ESRRAESR2 | |
| SCHEMBL28422184 | 0.70 | TDP1 (0.44) | ALDH1A1 | |
| SCHEMBL18935943 | 0.69 | CYP2A6 (0.43) | ALDH1A1 | |
| SCHEMBL9798193 | 0.67 | ALDH1A1 (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1084330-C | Cydic amide derivatives | OTSUKA PHARMA CO LTD (JP) | 2002-05-08 | — | — | CN | disclosed |
| EP-0719258-B1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| US-5786367-A | OXYGEN SCAVENGERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |
| CN-1130377-A | Cyclic amide derivatives | OTSUKA PHARMA CO LTD (JP) | 1996-09-04 | — | — | CN | disclosed |
| EP-0719258-A1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-03 | — | — | EP | disclosed |
| WO-1996002508-A1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-01 | — | — | WO | disclosed |