SCHEMBL4020967

SCHEMBL4020967

[CH2]c1ccc(C=C)c(Cl)c1

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50
TTR P02766 3/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL109034 0.78 TDP1 (0.60) ALDH1A1TDP1
SCHEMBL29376510 0.78 TDP1 (0.60) ALDH1A1TDP1
SCHEMBL7844640 0.77 ALDH1A1 (0.33) ALDH1A1
SCHEMBL2439383 0.76 ALDH1A1 (0.50) ALDH1A1TTRTDP1
Hydrogen Sulfide SCHEMBL29194425 0.76 TDP1 (0.58) ALDH1A1TDP1
SCHEMBL6814617 0.74 CYP3A4 (0.52) ALDH1A1TTRTDP1
SCHEMBL10800709 0.74 ALDH1A1 (0.48) ALDH1A1TTRTDP1
SCHEMBL139560 0.74 GABRA1 (0.50) ALDH1A1TTRTDP1
SCHEMBL7712097 0.74 ALDH1A1 (0.48) ALDH1A1TTRTDP1
SCHEMBL9996756 0.74 ALDH1A1 (0.48) ALDH1A1TTRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9150666-B2 Hydrolytically stable, hydrophilic adhesion-promoting monomers and polymers made therefrom ADA FOUNDATION (US) 2015-10-06 US claimed
WO-2009099824-A1 HYDROLYTICALLY STABLE, HYDROPHILIC ADHESION-PROMOTING MONOMERS AND POLYMERS MADE THEREFROM ADA FOUNDATION (US) 2009-08-13 WO claimed
US-20090188622-A1 Hydrolytically Stable, Hydrophilic Adhesion-Promoting Monomers and Polymers Made Therefrom ADA FOUNDATION (US) 2009-07-30 US claimed
US-9150666-B2 Hydrolytically stable, hydrophilic adhesion-promoting monomers and polymers made therefrom ADA FOUNDATION (US) 2015-10-06 US disclosed
WO-2009099824-A1 HYDROLYTICALLY STABLE, HYDROPHILIC ADHESION-PROMOTING MONOMERS AND POLYMERS MADE THEREFROM ADA FOUNDATION (US) 2009-08-13 WO disclosed
US-20090188622-A1 Hydrolytically Stable, Hydrophilic Adhesion-Promoting Monomers and Polymers Made Therefrom ADA FOUNDATION (US) 2009-07-30 US disclosed