SCHEMBL784481

SCHEMBL784481

N#CCc1ncc(C(F)(F)F)cc1Cl

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.54
TDP1 Q9NUW8 1/20 0.54
KMT2A Q03164 4/20 0.49
ALDH1A1 P00352 4/20 0.48
HTT P42858 2/20 0.48
GAA P10253 1/20 0.48
GLA P06280 1/20 0.45
MEN1 O00255 3/20 0.44
NPSR1 Q6W5P4 1/20 0.44
RAB9A P51151 1/20 0.44
PKM P14618 1/20 0.44
PLAU P00749 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6026121 0.98 L3MBTL1 (0.52) L3MBTL1TDP1KMT2AALDH1A1HTT
SCHEMBL30748276 0.84 L3MBTL1 (0.51) L3MBTL1TDP1KMT2AALDH1A1HTT
SCHEMBL29144635 0.84 L3MBTL1 (0.51) L3MBTL1TDP1KMT2AALDH1A1HTT
SCHEMBL3928008 0.81 L3MBTL1 (0.49) L3MBTL1TDP1KMT2AALDH1A1HTT
SCHEMBL24147641 0.81 POLQ (0.43) L3MBTL1TDP1KMT2AALDH1A1HTT
SCHEMBL25982779 0.81 AGBL2 (0.41) L3MBTL1TDP1KMT2AALDH1A1HTT
SCHEMBL24147640 0.80 AGBL2 (0.40) L3MBTL1TDP1KMT2AALDH1A1HTT
SCHEMBL3208283 0.79 TDP1 (0.59) L3MBTL1TDP1KMT2AALDH1A1HTT
SCHEMBL31255154 0.79 TDP1 (0.59) L3MBTL1TDP1KMT2AALDH1A1HTT
SCHEMBL11982024 0.77 TDP1 (0.58) L3MBTL1TDP1KMT2AALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026099838-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF FLUOPYRAM BEST AGROLIFE LIMITED (IN) 2026-05-15 WO claimed
CN-117417293-B Synthesis method of fluopyram 齐鲁晟华制药有限公司 2024-03-19 CN claimed
CN-117417293-A Synthesis method of fluopyram 齐鲁晟华制药有限公司 2024-01-19 CN claimed
CN-112552231-B Synthetic method of 2- (3-chloro-5- (trifluoromethyl) pyridine-2-yl) ethylamine 南京正荣医药化学有限公司 2022-03-11 CN claimed
US-10766859-B2 Catalytic hydrogenation of nitriles BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-09-08 US claimed
CN-108863915-B Synthesis method of fluopyram intermediate 2- [ 3-chloro-5 (trifluoromethyl) pyridine-2-yl ] acetonitrile 山东省农药科学研究院 2020-04-24 CN claimed
CN-122079876-A Fluopicola strain method for synthesizing amide 2026-05-26 CN disclosed
WO-2026099838-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF FLUOPYRAM BEST AGROLIFE LIMITED (IN) 2026-05-15 WO disclosed
CN-120441476-A Synthesis method of 2- (3-chloro-5- (trifluoromethyl) pyridin-2-yl) acetonitrile 天津均凯农业科技有限公司 2025-08-08 CN disclosed
CN-120441476-A Synthesis method of 2- (3-chloro-5- (trifluoromethyl) pyridin-2-yl) acetonitrile 天津均凯农业科技有限公司 2025-08-08 CN disclosed
CN-119684204-A Preparation method of fluopyram intermediate 顺毅南通化工有限公司 2025-03-25 CN disclosed
CN-119219553-A Synthesis method of 3-chloro-2-aminoethyl-5-trifluoromethyl pyridine 江苏快达农化股份有限公司 2024-12-31 CN disclosed
CN-118988227-A Composite stirring set and reactor comprising same 兰升生物科技集团股份有限公司 2024-11-22 CN disclosed
WO-2005058828-A1 2-PYRIDINYLETHYLBENZAMIDE DERIVATIVES BAYER CROPSCIENCE S.A. (FR) 2005-06-30 WO disclosed
EP-1548007-A1 2-Pyridinylethylcarboxamide derivatives and their use as fungicides Bayer CropScience S.A. (FR) 2005-06-29 EP disclosed
EP-1531673-A2 NOVEL 2-PYRIDYLETHYLBENZAMIDE DERIVATIVE Bayer CropScience S.A. (FR) 2005-05-25 EP disclosed
WO-2004074280-A1 PYRIDINE DERIVATIVES AS FUNGICIDAL COMPOUNDS BAYER CROPSCIENCE SA (FR) 2004-09-02 WO disclosed
EP-1449841-A1 New fungicidal compounds Bayer CropScience SA (FR) 2004-08-25 EP disclosed
WO-2004016088-A2 NOVEL 2-PYRIDYLETHYLBENZAMIDE DERIVATIVE BAYER CROPSCIENCE S.A. (FR) 2004-02-26 WO disclosed
EP-1389614-A1 Novel N-[2-(2-Pyridyl)ethyl]benzamide derivatives as fungicides Bayer CropScience S.A. (FR) 2004-02-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10766859-B2 Catalytic hydrogenation of nitriles HNMT, NUP50, HCN2 L3MBTL1 4449/4885TDP1 1398/4885KMT2A 1306/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.