Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14920461 | 0.83 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MAPK1GAACYP3A4 | |
| SCHEMBL14921072 | 0.78 | GLA (0.52) | ALDH1A1GLAHPGDSMN1; SMN2MAPK1 | |
| SCHEMBL7536561 | 0.77 | PLAU (0.47) | ALDH1A1SMN1; SMN2GAACYP3A4CYP2C19 | |
| SCHEMBL4410035 | 0.77 | ALDH1A1 (0.42) | ALDH1A1GLAHPGDSMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL6157994 | 0.76 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2GAACYP3A4CYP2C19 | |
| SCHEMBL3926835 | 0.75 | HPGD (0.42) | ALDH1A1GLAHPGDSMN1; SMN2MAPK1 | |
| SCHEMBL28718148 | 0.75 | MAPK1 (0.52) | ALDH1A1GLAHPGDSMN1; SMN2MAPK1 | |
| SCHEMBL14920829 | 0.75 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MAPK1GAACYP3A4 | |
| SCHEMBL12871592 | 0.74 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MAPK1GAACYP3A4 | |
| SCHEMBL6158224 | 0.73 | MEN1 (0.55) | ALDH1A1GLAHPGDSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071517-A1 | 2-PYRIDINYLETHYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER SAS (FR) | 2012-03-22 | — | — | US | disclosed |
| US-8071627-B2 | 2-pyridinylethylcarboxamide derivatives and their use as fungicides | BAYER SAS (FR) | 2011-12-06 | — | — | US | disclosed |
| US-7572818-B2 | Fungicides; N-{2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethyl}-2-trifluoromethylbenzamide; -{2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethyl}-2-iodobenzamide; -{2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethyl}-2-bromobenzamide | BAYER CROPSCIENCE S.A. (FR) | 2009-08-11 | — | — | US | disclosed |
| US-7560567-B2 | 2-pyridinylethylbenzamide derivatives | BAYER CROPSCIENCE S.A. (FR) | 2009-07-14 | — | — | US | disclosed |
| US-20090088456-A1 | 2-Pyridinylethylcarboxamide derivatives and their use as Fugicides | BAYER CROPSCIENCE S.A. | 2009-04-02 | — | — | US | disclosed |
| US-20070099965-A1 | 2-Pyridinylethylbenzamide derivatives | BAYER SAS (FR) | 2007-05-03 | — | — | US | disclosed |
| US-20050234110-A1 | Novel 2-pyridylethylbenzamide derivative | BAYER SAS (FR) | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088456-A1 | 2-Pyridinylethylcarboxamide derivatives and their use as Fugicides | PFAS, CYP4F2, FPGS | ALDH1A1 1119/4885GLA 529/4885HPGD 992/4885 |
| US-20050234110-A1 | Novel 2-pyridylethylbenzamide derivative | PNPO, PAH, CNPY2 | ALDH1A1 2346/4885GLA 1133/4885HPGD 708/4885 |
| US-20120071517-A1 | 2-PYRIDINYLETHYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | CYP1A2, CYP51A1, CYP3A5 | ALDH1A1 831/4885GLA 785/4885HPGD 2893/4885 |
| US-20070099965-A1 | 2-Pyridinylethylbenzamide derivatives | CYP1A2, CYP4B1, CYP4F2 | ALDH1A1 772/4885GLA 196/4885HPGD 1397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.