Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12501761 | 0.73 | MEN1 (0.77) | MEN1KMT2ASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL784514 | 0.73 | ALDH1A1 (0.46) | MEN1KMT2ASMN1; SMN2MAPTGAA | |
| SCHEMBL14920461 | 0.71 | ALDH1A1 (0.48) | SMN1; SMN2MAPTGAALMNAPOLB | |
| SCHEMBL526159 | 0.70 | KMT2A (0.59) | MEN1KMT2ASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL21950 | 0.70 | KMT2A (0.61) | MEN1KMT2ASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL29356683 | 0.70 | KMT2A (0.61) | MEN1KMT2ASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL15286566 | 0.70 | KMT2A (0.61) | MEN1KMT2ASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL7536561 | 0.69 | PLAU (0.47) | SMN1; SMN2MAPTGAALMNAPOLB | |
| Hydrochloric Acid SCHEMBL6157994 | 0.68 | ALDH1A1 (0.46) | SMN1; SMN2MAPTGAALMNAPOLB | |
| SCHEMBL526160 | 0.68 | GLA (0.59) | MEN1KMT2ASMN1; SMN2MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204322-B1 | FUNGICIDES | AVENTIS CROPSCIENCE GMBH (DE) | 2005-02-09 | — | — | EP | disclosed |
| US-6630495-B1 | Compound containing 2-pyridyl or its N-oxide | BAYER CROPSCIENCE GMBH (DE) | 2003-10-07 | — | — | US | disclosed |