Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.55 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.55 |
| ▸ | HINT1 | P49773 | 7/20 | 0.52 |
| ▸ | GSK3A | P49840 | 2/20 | 0.51 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.51 |
| ▸ | PNP | P00491 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.47 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.45 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26808474 | 1.00 | TAS1R3 (0.55) | TAS1R3TAS1R1HINT1GSK3ARPS6KA3 | |
| SCHEMBL16866669 | 0.93 | TAS1R3 (0.55) | TAS1R3TAS1R1HINT1GSK3ARPS6KA3 | |
| SCHEMBL784394 | 0.92 | TAS1R3 (0.55) | TAS1R3TAS1R1HINT1GSK3ARPS6KA3 | |
| SCHEMBL26808255 | 0.88 | HINT1 (0.52) | TAS1R3TAS1R1HINT1GSK3ARPS6KA3 | |
| SCHEMBL26808390 | 0.88 | HINT1 (0.52) | TAS1R3TAS1R1HINT1GSK3ARPS6KA3 | |
| SCHEMBL16870493 | 0.87 | TAS1R3 (0.57) | TAS1R3TAS1R1HINT1GSK3ARPS6KA3 | |
| SCHEMBL26808568 | 0.86 | HINT1 (0.51) | TAS1R3TAS1R1HINT1GSK3ARPS6KA3 | |
| SCHEMBL794488 | 0.86 | TAS1R3 (0.55) | TAS1R3TAS1R1HINT1GSK3ARPS6KA3 | |
| SCHEMBL25505210 | 0.86 | TAS1R3 (0.44) | TAS1R3TAS1R1HINT1GSK3ARPS6KA3 | |
| SCHEMBL29972968 | 0.85 | TAS1R3 (0.62) | TAS1R3TAS1R1HINT1GSK3ARPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264610-A1 | AZIDO NUCLEOSIDES AND NUCLEOTIDE ANALOGS | ALIOS BIOPHARMA INC (US) | 2016-09-15 | — | — | US | disclosed |
| US-9346848-B2 | Azido nucleosides and nucleotide analogs | ALIOS BIOPHARMA, INC. (US) | 2016-05-24 | — | — | US | disclosed |
| US-20150183819-A1 | AZIDO NUCLEOSIDES AND NUCLEOTIDE ANALOGS | ALIOS BIOPHARMA, INC. | 2015-07-02 | — | — | US | disclosed |
| US-8877731-B2 | Azido nucleosides and nucleotide analogs | ALIOS BIOPHARMA, INC. (US) | 2014-11-04 | — | — | US | disclosed |
| US-20120070415-A1 | AZIDO NUCLEOSIDES AND NUCLEOTIDE ANALOGS | ALIOS BIOPHARMA, INC. (US) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264610-A1 | AZIDO NUCLEOSIDES AND NUCLEOTIDE ANALOGS | PNP, ADA, ADAR | TAS1R3 2640/4885TAS1R1 2363/4885HINT1 121/4885 |
| US-20120070415-A1 | AZIDO NUCLEOSIDES AND NUCLEOTIDE ANALOGS | PNP, ADA, ADAR | TAS1R3 2640/4885TAS1R1 2363/4885HINT1 121/4885 |
| US-20150183819-A1 | AZIDO NUCLEOSIDES AND NUCLEOTIDE ANALOGS | PNP, ADA, ADAR | TAS1R3 2640/4885TAS1R1 2363/4885HINT1 121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.