Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30533387 | 0.83 | BRD4 (0.51) | HCRTR1HCRTR2BRD4KDM4EMYC | |
| SCHEMBL1671337 | 0.83 | BRD4 (0.51) | HCRTR1HCRTR2BRD4KDM4EMYC | |
| SCHEMBL69464 | 0.75 | SLC6A3 (0.67) | SLC6A3SLC6A4KDM4EPOLBATM | |
| SCHEMBL1586163 | 0.74 | SLC6A3 (0.54) | SLC6A3SLC6A4KDM4EPOLBATM | |
| Hydrochloric Acid SCHEMBL4345829 | 0.73 | BRD4 (0.57) | HCRTR1HCRTR2BRD4KDM4EHSD17B10 | |
| SCHEMBL28050388 | 0.73 | BRD4 (0.50) | BRD4KDM4ELMNATDP1ALDH1A1 | |
| SCHEMBL7845741 | 0.73 | SMN1; SMN2 (0.56) | KDM4ELMNATSHRTDP1ALDH1A1 | |
| SCHEMBL877718 | 0.73 | BRD4 (0.53) | HCRTR1HCRTR2BRD4KDM4EPOLB | |
| SCHEMBL29790416 | 0.72 | LMNA (0.57) | KDM4EPOLBATMLMNATSHR | |
| SCHEMBL13587950 | 0.72 | BRD4 (0.56) | HCRTR1HCRTR2BRD4KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850924-B1 | Aromatic diselenides and selenosulphides for use as antioxidant agents | OXIS ISLE OF MAN LTD (GB) | 2001-03-14 | — | — | EP | disclosed |
| US-6040328-A | ANTIOXIDANT AGENTS HAVING CYTOPROTECTING ACTIVITY, AND WATER SOLUBLE | OXIS INTERNATIONAL S.A. (US) | 2000-03-21 | — | — | US | disclosed |
| US-5973009-A | ANTIOXIDANT AND CYTOPROTECTING ACTIVITY | OXIS INTERNATIONAL S.A. (US) | 1999-10-26 | — | — | US | disclosed |
| EP-0850924-A1 | Aromatic diselenides and selenosulphides for use as antioxidant agents | OXIS Isle of Man, Limited (GB) | 1998-07-01 | — | — | EP | disclosed |