Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11374945 | 0.97 | ALDH1A1 (0.42) | ALDH1A1TP53KDM4EGMNNLMNA | |
| SCHEMBL13809529 | 0.89 | ALDH1A1 (0.37) | ALDH1A1TP53KDM4EGMNNLMNA | |
| SCHEMBL16753944 | 0.88 | THRB (0.32) | — | |
| SCHEMBL1111243 | 0.87 | ALDH1A1 (0.39) | ALDH1A1TP53KDM4EGMNNLMNA | |
| SCHEMBL11002215 | 0.87 | SHBG (0.41) | ALDH1A1TP53KDM4EGMNNLMNA | |
| SCHEMBL16281688 | 0.87 | ALDH1A1 (0.44) | ALDH1A1TP53KDM4EGMNNLMNA | |
| SCHEMBL11002831 | 0.84 | SHBG (0.48) | ALDH1A1TP53KDM4EGMNNLMNA | |
| SCHEMBL11001588 | 0.83 | SHBG (0.39) | ALDH1A1EPHX1SHBG | |
| SCHEMBL10999554 | 0.82 | ALDH1A1 (0.36) | ALDH1A1TP53KDM4EGMNNLMNA | |
| SCHEMBL10710749 | 0.82 | SHBG (0.38) | LMNAEPHX1SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767790-B1 | CONDENSED IMIDAZOLE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-12-12 | — | — | EP | disclosed |
| CN-1046725-C | fused imidazole compounds, their preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-11-24 | — | — | CN | disclosed |
| US-5840732-A | ANTIDIABETIC AGENTS, AUTOIMMUNE DISEASES OR IMMUNOSUPPRESSANTS | TAKEDA CHEMICAL INDUSTRIES LTD. (JP) | 1998-11-24 | — | — | US | disclosed |
| CN-1151161-A | fused imidazole compounds, their preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-06-04 | — | — | CN | disclosed |
| EP-0767790-A1 | CONDENSED IMIDAZOLE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-04-16 | — | — | EP | disclosed |
| WO-1995035296-A1 | CONDENSED IMIDAZOLE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-12-28 | — | — | WO | disclosed |