Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | TNKS | O95271 | 1/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14117693 | 0.97 | ADRB1 (0.63) | ADRB1MAPTNPC1KCNH2DRD2 | |
| SCHEMBL9831116 | 0.87 | ADRB1 (0.55) | ADRB1MAPTNPC1KCNH2DRD2 | |
| SCHEMBL11074672 | 0.82 | ADRB1 (0.76) | ADRB1MAPTNPC1KCNH2DRD2 | |
| SCHEMBL10690612 | 0.81 | ADRB1 (0.59) | ADRB1MAPTNPC1ALOX5POLB | |
| SCHEMBL23675047 | 0.79 | ADRB1 (0.71) | ADRB1MAPTNPC1KCNH2DRD2 | |
| SCHEMBL3051915 | 0.79 | ADRB1 (0.71) | ADRB1MAPTNPC1KCNH2DRD2 | |
| SCHEMBL30255158 | 0.79 | ADRB1 (0.71) | ADRB1MAPTNPC1KCNH2DRD2 | |
| SCHEMBL12301330 | 0.78 | ALOX5 (0.56) | ADRB1MAPTNPC1KCNH2DRD2 | |
| SCHEMBL1372924 | 0.78 | ADRB1 (0.65) | ADRB1MAPTNPC1KCNH2DRD2 | |
| SCHEMBL738227 | 0.78 | HTR3E (0.59) | ADRB1MAPTDRD2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802173-B1 | Process for producing heterocylic aromatic amine or arylamine | TOSOH CORP (JP) | 2001-12-19 | — | — | EP | disclosed |
| US-5929281-A | REACTING A HETROCYCLIC AROMATIC HALIDE WITH AN AMINE COMPOUND IN PRESENCE OF A BASE USING A TRI-TERT-BUTYLPHOSPHINE AND PALLADIUM COMPOUND CATALYST TO FORM HETEROCYCLIC AROMATIC AMINE COMPOUNDS | TOSOH CORPORATION (JP) | 1999-07-27 | — | — | US | disclosed |
| EP-0802173-A1 | Process for producing heterocylic aromatic amine or arylamine | Tosoh Corporation (JP) | 1997-10-22 | — | — | EP | disclosed |