Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAT1 | O14929 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.40 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.40 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.40 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.40 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.40 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.40 |
| ▸ | AGER | Q15109 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7845162 | 0.84 | GABRA1 (0.39) | HAT1EP300GABRA1GABRB2CFTR | |
| SCHEMBL7834749 | 0.84 | GAA (0.48) | GABRA1GABRB2CFTRPRKAB2PRKAG1 | |
| SCHEMBL7843026 | 0.82 | GABRA1 (0.45) | GABRA1GABRB2CFTRPRKAB2PRKAG1 | |
| SCHEMBL6686020 | 0.81 | GABRA1 (0.48) | HAT1EP300GABRA1GABRB2CFTR | |
| SCHEMBL7841512 | 0.79 | ALDH1A1 (0.46) | — | |
| SCHEMBL6667391 | 0.78 | KDM4E (0.41) | HAT1EP300GABRA1GABRB2CFTR | |
| SCHEMBL7845316 | 0.77 | HSD17B10 (0.44) | GABRA1GABRB2CFTR | |
| SCHEMBL7843880 | 0.76 | ALDH1A1 (0.45) | — | |
| SCHEMBL7845846 | 0.74 | GAA (0.51) | GABRA1GABRB2CFTR | |
| SCHEMBL6961431 | 0.73 | ALDH1A1 (0.44) | GABRA1GABRB2CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140850-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040561-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-13 | — | — | WO | disclosed |