Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846009 | 0.89 | HDAC1 (0.37) | ALDH1A1KMT2A | |
| SCHEMBL7835036 | 0.81 | CA12 (0.41) | ALDH1A1 | |
| SCHEMBL7494152 | 0.80 | TSHR (0.39) | ALDH1A1KMT2A | |
| SCHEMBL7505066 | 0.78 | — | — | |
| SCHEMBL3580870 | 0.77 | POLB (0.44) | ALDH1A1KMT2A | |
| SCHEMBL1020598 | 0.75 | IL1B (0.48) | ALDH1A1KMT2A | |
| SCHEMBL1019418 | 0.73 | IL1B (0.42) | — | |
| SCHEMBL7844874 | 0.71 | IL1B (0.42) | ALDH1A1 | |
| SCHEMBL7835032 | 0.69 | CNR1 (0.36) | — | |
| SCHEMBL2035744 | 0.69 | CNR1 (0.49) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821685-B1 | INDOLE-3-CARBONYL AND INDOLE-3-SULFONYL DERIVATIVES AS PLATELET ACTIVATING FACTOR ANTAGONISTS | ABBOTT LAB (US) | 2001-10-04 | — | — | EP | disclosed |
| EP-0821685-A1 | INDOLE-3-CARBONYL AND INDOLE-3-SULFONYL DERIVATIVES AS PLATELET ACTIVATING FACTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 1998-02-04 | — | — | EP | disclosed |
| WO-1996033196-A1 | INDOLE-3-CARBONYL AND INDOLE-3-SULFONYL DERIVATIVES AS PLATELET ACTIVATING FACTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 1996-10-24 | — | — | WO | disclosed |
| US-5567711-A | Indole-3-carbonyl and indole-3-sulfonyl derivatives as platelet activating factor antagonists | ABBOTT LABORATORIES (US) | 1996-10-22 | — | — | US | disclosed |