Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL704312 | 0.84 | — | — | |
| SCHEMBL4784026 | 0.80 | TSHR (0.63) | TSHRALDH1A1TDP1 | |
| SCHEMBL30578097 | 0.78 | — | — | |
| SCHEMBL705843 | 0.77 | — | — | |
| SCHEMBL58489 | 0.75 | TSHR (0.44) | TSHRALDH1A1 | |
| SCHEMBL23701168 | 0.73 | TSHR (0.50) | TSHRALDH1A1 | |
| SCHEMBL3767966 | 0.73 | TSHR (0.50) | TSHRALDH1A1 | |
| SCHEMBL502450 | 0.73 | TSHR (0.50) | TSHRALDH1A1 | |
| SCHEMBL3773266 | 0.71 | — | — | |
| SCHEMBL28965111 | 0.71 | DNM1 (0.43) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714898-B1 | PYRAZOLO [1,5-a]PYRIMIDINE DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2001-11-14 | — | — | EP | disclosed |
| US-5707997-A | ANALGESICS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0714898-A1 | PYRAZOLO [1,5-a]PYRIMIDINE DERIVATIVE | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1996-06-05 | — | — | EP | disclosed |