Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846408 | 0.81 | PKM (0.34) | GAASMN1; SMN2 | |
| SCHEMBL7835902 | 0.80 | F2R (0.40) | GAASMN1; SMN2 | |
| SCHEMBL7844391 | 0.79 | CREBBP (0.41) | GAA | |
| SCHEMBL7844718 | 0.73 | ACHE (0.36) | GAASMN1; SMN2 | |
| SCHEMBL7842879 | 0.67 | ALDH1A1 (0.41) | GAASMN1; SMN2 | |
| SCHEMBL7847789 | 0.65 | SMN1; SMN2 (0.41) | GAASMN1; SMN2 | |
| SCHEMBL7845972 | 0.64 | ALDH1A1 (0.44) | GAA | |
| SCHEMBL23857271 | 0.58 | MAPT (0.56) | GAACACNA1S | |
| SCHEMBL6384868 | 0.58 | KDM4E (0.56) | GAA | |
| SCHEMBL30882936 | 0.58 | MAPT (0.56) | GAACACNA1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820455-B1 | 5H, 10H-IMIDAZO [1,2-a]INDENO [1,2-e]PYRAZIN-4-ONE DERIVATIVES, PREPARATION THEREOF, AND DRUGS CONTAINING SAID DERIVATIVES | AVENTIS PHARMA SA (FR) | 2001-10-31 | — | — | EP | disclosed |