SCHEMBL4515369

SCHEMBL4515369

c1ccc2c(c1)[nH]c1c3ccccc3[nH]c21

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.67
GPR3 P46089 2/20 0.67
HSD17B10 Q99714 2/20 0.67
KIF11 P52732 4/20 0.56
KDM4E B2RXH2 4/20 0.55
GLA P06280 2/20 0.55
HPGD P15428 2/20 0.55
AHR P35869 2/20 0.55
LMNA P02545 2/20 0.55
GAA P10253 1/20 0.55
HTT P42858 1/20 0.55
ATM Q13315 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
KMT2A Q03164 5/20 0.54
MEN1 O00255 4/20 0.54
MAPT P10636 3/20 0.54
GABRP O00591 1/20 0.54
GABRD O14764 1/20 0.54
GABRA1 P14867 1/20 0.54
GABRB1 P18505 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL191347 0.88 KIF11 (0.71) ALDH1A1GPR3HSD17B10KIF11KDM4E
SCHEMBL29378455 0.88 KIF11 (0.71) ALDH1A1GPR3HSD17B10KIF11KDM4E
SCHEMBL7846565 0.85 ALDH1A1 (0.67) ALDH1A1GPR3HSD17B10KDM4EGLA
SCHEMBL30704463 0.85 ALDH1A1 (0.67) ALDH1A1GPR3HSD17B10KDM4EGLA
SCHEMBL4069254 0.83 PARP1 (0.65) ALDH1A1GPR3HSD17B10KIF11KDM4E
SCHEMBL29533066 0.82 CHEK1 (0.65) ALDH1A1GPR3HSD17B10KIF11KDM4E
SCHEMBL30741432 0.82 CHEK1 (0.65) ALDH1A1GPR3HSD17B10KIF11KDM4E
SCHEMBL13563976 0.82 KIF11 (0.78) ALDH1A1GPR3HSD17B10KIF11KDM4E
SCHEMBL12219428 0.82 CHEK1 (0.65) ALDH1A1GPR3HSD17B10KIF11KDM4E
SCHEMBL17228829 0.80 PRKCA (0.61) ALDH1A1GPR3HSD17B10KIF11KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3444257-B1 ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE BOE TECHNOLOGY GROUP CO LTD (CN) 2021-12-22 EP claimed
US-10886475-B2 Organic electroluminescent materials and organic electroluminescent devices BOE TECHNOLOGY GROUP CO., LTD. (CN) 2021-01-05 US claimed
EP-3444257-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE Boe Technology Group Co. Ltd. (CN) 2019-02-20 EP claimed
US-20180069183-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICES BOE TECHNOLOGY GROUP CO., LTD. (CN) 2018-03-08 US claimed
US-20230269998-A1 LIGHT EMITTING ELEMENT AND ORGANOMETALLIC COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-24 US disclosed
US-20230006146-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2023-01-05 US disclosed
EP-3444257-B1 ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE BOE TECHNOLOGY GROUP CO LTD (CN) 2021-12-22 EP disclosed
EP-3444257-B1 ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE BOE TECHNOLOGY GROUP CO LTD (CN) 2021-12-22 EP disclosed
US-20210193935-A1 P ACTIVE MATERIALS FOR ORGANIC PHOTOELECTRIC CONVERSION LAYERS IN ORGANIC PHOTODIODES SONY CORPORATION (JP) 2021-06-24 US disclosed
US-10886475-B2 Organic electroluminescent materials and organic electroluminescent devices BOE TECHNOLOGY GROUP CO., LTD. (CN) 2021-01-05 US disclosed
US-10886475-B2 Organic electroluminescent materials and organic electroluminescent devices BOE TECHNOLOGY GROUP CO., LTD. (CN) 2021-01-05 US disclosed
US-10807984-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-10-20 US disclosed
EP-1331010-A1 PREVENTIVES AND REMEDIES FOR CENTRAL NERVOUS SYSTEM DISEASES Takeda Chemical Industries, Ltd. (JP) 2003-07-30 EP disclosed
EP-1310490-A1 GPR14 ANTAGONIST Takeda Chemical Industries, Ltd. (JP) 2003-05-14 EP disclosed
EP-1308513-A1 USE OF POLYPEPTIDE Takeda Chemical Industries, Ltd. (JP) 2003-05-07 EP disclosed
US-6534496-B1 Prophylactic and/or therapeutic drug for obesity and obesity associated diseasestor diabetes with a reduced risk for central side effects and high universality in usage. Another object of the a lipolytic agent, or a prophylactic and/or TAKEDA CHEMICAL INDUSTRIES, INC. (JP) 2003-03-18 US disclosed
US-20020177593-A1 Agents and crystals for improving excretory potency of urinary bladder TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2002-11-28 US disclosed
EP-1118322-A1 DRUGS FOR IMPROVING VESICAL EXCRETORY STRENGTH Takeda Chemical Industries, Ltd. (JP) 2001-07-25 EP disclosed
US-5620973-A CHOLINESTERASE INHIBITOR; ALZHEIMER*S DISEASE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-04-15 US disclosed
EP-0655451-A1 Tetracyclic condensed heterocyclic compounds for the treatment of senile dementia TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-05-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230269998-A1 LIGHT EMITTING ELEMENT AND ORGANOMETALLIC COMPOUND FOR THE SAME CRY1, CRY2, NFE2L2 ALDH1A1 121/4885GPR3 4829/4885HSD17B10 2384/4885
US-20180069183-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICES SLC26A3, SLCO2A1, SLCO2B1 ALDH1A1 602/4885GPR3 1147/4885HSD17B10 700/4885
US-10886475-B2 Organic electroluminescent materials and organic electroluminescent devices SLC26A3, SLCO2A1, SLCO2B1 ALDH1A1 602/4885GPR3 1147/4885HSD17B10 700/4885
US-20020177593-A1 Agents and crystals for improving excretory potency of urinary bladder ACHE, BPHL, BCHE ALDH1A1 1185/4885GPR3 1696/4885HSD17B10 3205/4885
US-10807984-B2 Heterocyclic compound and organic light-emitting device including the same CRY1, CYP1A1, CYP1B1 ALDH1A1 28/4885GPR3 2360/4885HSD17B10 1366/4885
US-20230006146-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OCIAD2, OCIAD1 ALDH1A1 1842/4885GPR3 2556/4885HSD17B10 2762/4885
US-20210193935-A1 P ACTIVE MATERIALS FOR ORGANIC PHOTOELECTRIC CONVERSION LAYERS IN ORGANIC PHOTODIODES JUP, L1CAM, EPCAM ALDH1A1 2995/4885GPR3 4411/4885HSD17B10 4665/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.