SCHEMBL30704438

SCHEMBL30704438

Cc1ccc2[nH]c3c(=O)c4ccccc4[nH]c3c2c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.73
KMT2A Q03164 2/20 0.73
NPC1 O15118 2/20 0.73
POLB P06746 2/20 0.73
ABCB1 P08183 1/20 0.62
KDM4E B2RXH2 5/20 0.54
ALDH1A1 P00352 5/20 0.54
GLA P06280 3/20 0.54
GAA P10253 3/20 0.54
KIF11 P52732 1/20 0.51
CDK4 P11802 1/20 0.51
CCND1 P24385 1/20 0.51
CAMK2B Q13554 1/20 0.51
CAMK2G Q13555 1/20 0.51
CAMK2D Q13557 1/20 0.51
CAMK2A Q9UQM7 1/20 0.51
ROCK2 O75116 1/20 0.51
HPGD P15428 5/20 0.50
LMNA P02545 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27353440 1.00 MEN1 (0.73) MEN1KMT2ANPC1POLBABCB1
SCHEMBL13412884 0.86 MEN1 (0.65) MEN1KMT2ANPC1POLBABCB1
SCHEMBL17616019 0.84 MEN1 (1.00) MEN1KMT2ANPC1POLBABCB1
SCHEMBL13377717 0.83 MEN1 (0.58) MEN1KMT2ANPC1POLBABCB1
SCHEMBL7846565 0.82 ALDH1A1 (0.67) MEN1KMT2ANPC1POLBABCB1
SCHEMBL30704463 0.82 ALDH1A1 (0.67) MEN1KMT2ANPC1POLBABCB1
SCHEMBL5621445 0.82 ALDH1A1 (0.73) MEN1KMT2ANPC1POLBABCB1
SCHEMBL12039630 0.81 NPC1 (0.93) MEN1KMT2ANPC1POLBABCB1
SCHEMBL21972722 0.81 KIF11 (0.67) MEN1KMT2ANPC1POLBABCB1
SCHEMBL21972973 0.80 NPC1 (0.90) MEN1KMT2ANPC1POLBABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4543856-A1 BENZOCARBAZOLE DERIVATIVES AS INHIBITORS OF DRP1 Asha Therapeutics LLC (US) 2025-04-30 EP disclosed
WO-2023249965-A1 BENZOCARBAZOLE DERIVATIVES AS INHIBITORS OF DRP1 ASHA THERAPEUTICS LLC (US) 2023-12-28 WO disclosed