Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | CTSS | P25774 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5745010 | 0.93 | MEN1 (0.67) | FAAHMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL18607541 | 0.90 | MEN1 (0.68) | MEN1KMT2ACYP1A2CYP2C19MTNR1A | |
| SCHEMBL30561254 | 0.90 | MEN1 (0.61) | FAAHMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL22038251 | 0.90 | MEN1 (0.61) | FAAHMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL22038231 | 0.89 | MTNR1A (0.60) | MEN1KMT2AMTNR1A | |
| SCHEMBL22038614 | 0.88 | FAAH (0.51) | FAAHIDO1MEN1KMT2ACYP1A2 | |
| SCHEMBL22039141 | 0.87 | MAPT (0.61) | FAAHMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL9797969 | 0.87 | LMNA (0.53) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL30561257 | 0.87 | MAPT (0.61) | FAAHMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL22038232 | 0.87 | MTNR1A (0.50) | FAAHIDO1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1335845-A | 3,4-dihydro-2H-benzo[1,4] oxazinyl-methyl [3-(1H-indol-3-yl)-alkyl]-amines | AMERICAN HOME PROD (US) | 2002-02-13 | — | — | CN | disclosed |
| EP-1071683-A1 | NEW COMPOUNDS | AstraZeneca AB (SE) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999046264-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | disclosed |