(Chloromethyl)Benzene

(Chloromethyl)Benzene

SCHEMBL7846835

C=C(CC)C(=O)ON.ClCc1ccccc1

nearest known ligand 0.36

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.36
MAPT P10636 2/20 0.36
SRR Q9GZT4 2/20 0.36
MAPK1 P28482 2/20 0.35
KMT2A Q03164 3/20 0.34
TDP1 Q9NUW8 2/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A3 Q01959 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
GAA P10253 1/20 0.34
RAB9A P51151 1/20 0.34
TSHR P16473 3/20 0.33
CYP1A2 P05177 1/20 0.33
MEN1 O00255 1/20 0.33
ABCC3 O15438 1/20 0.33
PLIN1 O60240 1/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
GSTA1 P08263 1/20 0.33
GSTP1 P09211 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Chloromethyl)Benzene SCHEMBL5491487 0.82 EGFR (0.36) ALDH1A1MAPTSMN1; SMN2RAB9ALMNA
(Chloromethyl)Benzene SCHEMBL28381338 0.78 MTNR1A (0.37) ALDH1A1KMT2AGAARAB9AMEN1
Chloromethane SCHEMBL28149021 0.77 ALDH1A1 (0.30) ALDH1A1TSHR
SCHEMBL994740 0.77
SCHEMBL27498965 0.76 CES1 (0.48) ALDH1A1SRRMAPK1KMT2ATSHR
(Chloromethyl)Benzene SCHEMBL5962068 0.76 ALDH1A1 (0.37) ALDH1A1SRRMAPK1KMT2ATDP1
(Chloromethyl)Benzene SCHEMBL29136077 0.76 PLA2G10 (0.42) ALDH1A1KMT2ASMN1; SMN2LMNATP53
(Chloromethyl)Benzene SCHEMBL27624896 0.75 AKR1B1 (0.50) ALDH1A1MAPK1KMT2ATDP1SLC6A3
Hydrochloric Acid SCHEMBL27871589 0.75
(Chloromethyl)Benzene SCHEMBL27460600 0.74 HSD11B1 (0.46) ALDH1A1MAPK1KMT2ATDP1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019050835-A1 TERPOLYMERS FOR OIL SANDS TAILINGS TREATMENT KEMIRA OYJ (FI) 2019-03-14 WO disclosed
US-6177017-B1 COMPLEXING WITH 1,4-DIAZABICYCLO(2.2.2) OCTANE POLYMERS NALCO CHEMICAL COMPANY 2001-01-23 US disclosed
US-6177017-B1 COMPLEXING WITH 1,4-DIAZABICYCLO(2.2.2) OCTANE POLYMERS NALCO CHEMICAL COMPANY 2001-01-23 US disclosed
US-6114484-A REMOVAL OF METAL CYANIDES OR OXOANIONS FROM AQUEOUS STREAMS SUCH AS WASTE WATER STREAMS WITH COMPOUNDS CONTAINING 1,4-DIAZABICYCLO(2.2.2)OCTANE NALCO CHEMICAL COMPANY (US) 2000-09-05 US disclosed
US-6114484-A REMOVAL OF METAL CYANIDES OR OXOANIONS FROM AQUEOUS STREAMS SUCH AS WASTE WATER STREAMS WITH COMPOUNDS CONTAINING 1,4-DIAZABICYCLO(2.2.2)OCTANE NALCO CHEMICAL COMPANY (US) 2000-09-05 US disclosed