Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | RORA | P35398 | 2/20 | 0.46 |
| ▸ | RORC | P51449 | 2/20 | 0.46 |
| ▸ | RORB | Q92753 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | S100A4 | P26447 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5011561 | 1.00 | TDP1 (0.54) | TDP1L3MBTL1KDM4EMAPK1NPSR1 | |
| SCHEMBL18071858 | 1.00 | TDP1 (0.54) | TDP1L3MBTL1KDM4EMAPK1NPSR1 | |
| SCHEMBL11955368 | 0.99 | TDP1 (0.55) | TDP1L3MBTL1KDM4EMAPK1NPSR1 | |
| SCHEMBL80507 | 0.94 | TDP1 (0.61) | TDP1L3MBTL1KDM4EMAPK1NPSR1 | |
| SCHEMBL19728591 | 0.90 | TDP1 (0.47) | TDP1L3MBTL1KDM4EMAPK1NPSR1 | |
| SCHEMBL19728600 | 0.87 | TDP1 (0.43) | TDP1L3MBTL1KDM4EMAPK1NPSR1 | |
| SCHEMBL18071859 | 0.84 | TDP1 (0.41) | TDP1L3MBTL1KDM4EMAPK1NPSR1 | |
| SCHEMBL13038973 | 0.84 | ALDH1A1 (0.46) | TDP1L3MBTL1KDM4EMAPK1NPSR1 | |
| SCHEMBL10067790 | 0.83 | ALDH1A1 (0.58) | TDP1L3MBTL1KDM4EMAPK1NPSR1 | |
| SCHEMBL14365729 | 0.82 | KDM4E (0.51) | TDP1L3MBTL1KDM4ENPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6210783-B1 | COMPRISED OF SUPPORTING SUBSTRATE, A HEAT DISSIPATING COATING LAYER IN CONTACT WITH SUBSTRATE, WHEREIN COATING IS COMPRISED OF A HEAT DISSIPATING BINDER, AN ANTISTATIC COMPOUND, AN INK RECEIVER COATING COMPRISING BINDER, OXAZOLINE COMPOUND | XEROX CORPORATION | 2001-04-03 | — | — | US | disclosed |