Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC5R | P33032 | 3/20 | 0.61 |
| ▸ | MC1R | Q01726 | 3/20 | 0.61 |
| ▸ | TACR1 | P25103 | 3/20 | 0.55 |
| ▸ | ECE1 | P42892 | 2/20 | 0.49 |
| ▸ | HPGDS | O60760 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7062961 | 0.83 | TACR1 (0.76) | TACR1ECE1MEN1KMT2A | |
| SCHEMBL7846982 | 0.83 | BRS3 (0.60) | TACR1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL7064065 | 0.81 | TACR1 (0.68) | TACR1ECE1MAPTSMN1; SMN2HTT | |
| SCHEMBL7067777 | 0.81 | TACR1 (0.67) | TACR1ECE1 | |
| SCHEMBL29459408 | 0.80 | MC5R (0.84) | MC5RMC1RECE1HPGDSKMT2A | |
| SCHEMBL27923213 | 0.79 | KCNT1 (0.66) | MC5RMC1RECE1MAPTMEN1 | |
| SCHEMBL901464 | 0.79 | KCNT1 (0.66) | MC5RMC1RECE1MAPTMEN1 | |
| SCHEMBL7848668 | 0.78 | MAOB (0.46) | MC5RMC1RTACR1MAPTMEN1 | |
| SCHEMBL1711017 | 0.76 | ERAP2 (0.66) | MAPTPOLBERAP2HPGDMAPK1 | |
| SCHEMBL29519692 | 0.76 | MC5R (1.00) | MC5RMC1RKCNT1KDM4EMC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140914-A1 | NON-PEPTIDE NK1 RECEPTORS ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037462-A1 | NON-PEPTIDE NK1 RECEPTORS ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2000-06-29 | — | — | WO | disclosed |