Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.36 |
| ▸ | LHCGR | P22888 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847265 | 1.00 | KDM4E (0.40) | KDM4EALDH1A1MAPTL3MBTL1TP53 | |
| SCHEMBL7846734 | 0.88 | CNR1 (0.39) | PLAUHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7846731 | 0.88 | CNR1 (0.39) | PLAUHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL17560326 | 0.84 | HTR3E (0.55) | MAPTL3MBTL1SMN1; SMN2HTR3EHTR3B | |
| SCHEMBL7228914 | 0.82 | SIGMAR1 (0.41) | KDM4EALDH1A1MAPTL3MBTL1TP53 | |
| SCHEMBL7843889 | 0.82 | PLAU (0.37) | KDM4EALDH1A1MAPTPLAULMNA | |
| SCHEMBL7843891 | 0.82 | PLAU (0.37) | KDM4EALDH1A1MAPTPLAULMNA | |
| SCHEMBL7229573 | 0.81 | CCR1 (0.40) | KDM4EALDH1A1MAPTL3MBTL1TP53 | |
| Hydrochloric Acid SCHEMBL7229297 | 0.78 | TAAR1 (0.62) | KDM4EALDH1A1MAPTL3MBTL1TP53 | |
| SCHEMBL7842304 | 0.78 | TRPV1 (0.37) | LHCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1157022-A1 | PYRIDINE COMPOUNDS AND THEIR PHARMACEUTICAL USE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000049015-A1 | PYRIDINE COMPOUNDS AND THEIR PHARMACEUTICAL USE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-08-24 | — | — | WO | disclosed |