Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | STAT3 | P40763 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26485826 | 0.81 | RAB9A (0.78) | POLBMEN1KMT2AMAPTSTAT3 | |
| SCHEMBL8278816 | 0.80 | SMN1; SMN2 (0.60) | POLBKMT2ARAB9AGAAALDH1A1 | |
| SCHEMBL7838803 | 0.80 | LMNA (0.76) | POLBMEN1KMT2AMAPTGAA | |
| SCHEMBL7847985 | 0.79 | KMT2A (0.58) | POLBMEN1KMT2AMAPTRAB9A | |
| SCHEMBL7847723 | 0.79 | POLB (0.64) | POLBMEN1KMT2AMAPTRAB9A | |
| SCHEMBL7848175 | 0.78 | POLB (0.67) | POLBMEN1KMT2AMAPTGAA | |
| SCHEMBL7677886 | 0.78 | MEN1 (0.84) | MEN1KMT2AMAPTRAB9AGAA | |
| SCHEMBL17309683 | 0.77 | LMNA (0.57) | POLBKMT2AMAPTRAB9AGAA | |
| SCHEMBL7849208 | 0.77 | POLB (0.61) | POLBMEN1KMT2AMAPTRAB9A | |
| SCHEMBL13973308 | 0.76 | MAPT (0.74) | POLBMEN1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140914-A1 | NON-PEPTIDE NK1 RECEPTORS ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037462-A1 | NON-PEPTIDE NK1 RECEPTORS ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2000-06-29 | — | — | WO | disclosed |