SCHEMBL7847765

SCHEMBL7847765

O=[N+]([O-])c1[c]c([N+](=O)[O-])cc(C(F)(F)F)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
CYP3A4 P08684 3/20 0.52
TSHR P16473 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
HPGD P15428 1/20 0.52
ALOX15 P16050 1/20 0.52
HIF1A Q16665 1/20 0.52
TXNRD1 Q16881 1/20 0.52
TXNRD3 Q86VQ6 1/20 0.52
TXNRD2 Q9NNW7 1/20 0.52
PTPN5 P54829 1/20 0.43
MAPK1 P28482 3/20 0.41
MAPT P10636 6/20 0.39
LMNA P02545 3/20 0.39
HTT P42858 1/20 0.39
KIF11 P52732 2/20 0.38
GAA P10253 1/20 0.37
PLK1 P53350 1/20 0.37
KDM4E B2RXH2 1/20 0.37
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6223113 0.88 ALDH1A1 (0.46) ALDH1A1CYP3A4TSHRTDP1HPGD
SCHEMBL971971 0.87 ALDH1A1 (0.45) ALDH1A1CYP3A4TSHRTDP1HPGD
SCHEMBL1531196 0.87 CYP3A4 (0.53) ALDH1A1CYP3A4TSHRTDP1HPGD
SCHEMBL5379822 0.78 GABRA1 (0.39) ALDH1A1CYP3A4TSHRTDP1HPGD
SCHEMBL146794 0.76 ALDH1A1 (0.42) ALDH1A1CYP3A4TSHRTDP1HPGD
SCHEMBL6279366 0.75 CYP3A4 (0.41) ALDH1A1CYP3A4TSHRTDP1HPGD
SCHEMBL27792077 0.75 ALDH1A1 (0.41) ALDH1A1CYP3A4TSHRTDP1HPGD
SCHEMBL28195141 0.75 ATM (0.40) ALDH1A1TSHRTDP1HIF1ALMNA
SCHEMBL9998848 0.74 ALDH1A1 (0.31) ALDH1A1CYP3A4TSHRTDP1HPGD
SCHEMBL1996062 0.73 ALDH1A1 (0.55) ALDH1A1CYP3A4TSHRTDP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184577-A Phenyl ether meta-amide compound and application thereof 山东省农药科学研究院 2024-06-14 CN claimed
CN-105218645-B A kind of Caspofungin impurity C of high-purity high-yield0Preparation method 成都雅途生物技术有限公司 2018-08-07 CN claimed
CN-105218645-A A kind of Caspofungin impurity C of high-purity high-yield 0preparation method YACHT BIOTECHNOLOGY COMPANY 2016-01-06 CN claimed
US-4335133-A BACTERICIDES, FUNGICIDES CHEVRON RESEARCH COMPANY (US) 1982-06-15 US claimed
US-4271306-A FUNGICIDES, BACTERICIDES CHEVRON RESEARCH COMPANY (US) 1981-06-02 US claimed
CN-118184577-A Phenyl ether meta-amide compound and application thereof 山东省农药科学研究院 2024-06-14 CN disclosed
CN-112110985-B 6- (acetyl-Arg-Gly-Asp-AA-sulfhydryl) purine, synthesis, activity and application thereof 首都医科大学 2022-09-02 CN disclosed
CN-112110986-B 6-acetyl RGD mercaptopurine, synthesis thereof, activity of combination of 6-acetyl RGD mercaptopurine and cisplatin and application of 6-acetyl RGD mercaptopurine 首都医科大学 2022-04-22 CN disclosed
CN-112110986-A 6-acetyl RGD mercaptopurine, synthesis thereof, activity of combination of 6-acetyl RGD mercaptopurine and cisplatin and application of 6-acetyl RGD mercaptopurine 首都医科大学 2020-12-22 CN disclosed
CN-105218645-B A kind of Caspofungin impurity C of high-purity high-yield0Preparation method 成都雅途生物技术有限公司 2018-08-07 CN disclosed
CN-105218645-A A kind of Caspofungin impurity C of high-purity high-yield 0preparation method YACHT BIOTECHNOLOGY COMPANY 2016-01-06 CN disclosed
CN-103524441-A Compound comprising triazole structure, preparation method thereof and application of compound taken as weed killer UNIV CHINA AGRICULTURAL 2014-01-22 CN disclosed
EP-0731801-B1 SUBSTITUTED AMINOALKYLAMINOPYRIDINES BYK GULDEN LOMBERG CHEM FAB (DE) 2001-10-24 EP disclosed
US-5369116-A Polyfluorinated thiazoline derivative and chemical for controlling noxious organisms containing the same UBE INDUSTRIES, LTD. (JP) 1994-11-29 US disclosed
US-5288733-A Quinolylmethoxyphenylacetic acid acylamides and ureas BAYER AKTIENGESELLSCHAFT (DE) 1994-02-22 US disclosed
US-5266578-A Lipoxygenase inhibitors BAYER AKTIENGESELLSCHAFT (DE) 1993-11-30 US disclosed
EP-0096905-B1 PROCESS FOR THE PREPARATION OF GLYCOL ALDEHYDE SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1986-04-23 EP disclosed
EP-0096905-A1 Process for the preparation of glycol aldehyde SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1983-12-28 EP disclosed
US-4335133-A BACTERICIDES, FUNGICIDES CHEVRON RESEARCH COMPANY (US) 1982-06-15 US disclosed
US-4271306-A FUNGICIDES, BACTERICIDES CHEVRON RESEARCH COMPANY (US) 1981-06-02 US disclosed