Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.44 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.44 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847765 | 0.87 | ALDH1A1 (0.52) | ALDH1A1CYP3A4TSHRTDP1HPGD | |
| SCHEMBL6223113 | 0.80 | ALDH1A1 (0.46) | ALDH1A1CYP3A4TSHRTDP1HPGD | |
| SCHEMBL1531196 | 0.79 | CYP3A4 (0.53) | ALDH1A1CYP3A4TSHRTDP1HPGD | |
| SCHEMBL147633 | 0.76 | CES2 (0.37) | ALDH1A1CYP3A4TSHRTDP1HPGD | |
| SCHEMBL11750501 | 0.75 | ERN1 (0.34) | ALDH1A1CYP3A4 | |
| SCHEMBL909296 | 0.73 | TSHR (0.45) | ALDH1A1CYP3A4TSHRTDP1LMNA | |
| SCHEMBL28723924 | 0.72 | TSHR (0.44) | ALDH1A1CYP3A4TSHRTDP1MAPT | |
| SCHEMBL18230298 | 0.72 | ALDH1A1 (0.42) | ALDH1A1TSHRTDP1MAPK1 | |
| SCHEMBL11444409 | 0.69 | ALDH1A1 (0.66) | ALDH1A1CYP3A4TSHRTDP1HPGD | |
| SCHEMBL4577947 | 0.69 | ALDH1A1 (0.38) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8568685-B2 | Separation of nanostructures | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-10-29 | — | — | US | disclosed |
| US-20110011773-A1 | Separation of Nanostructures | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2011-01-20 | — | — | US | disclosed |
| CN-101910049-A | Separation of nanostructures | MASSACHUSETTS INST TECHNOLOGY | 2010-12-08 | — | — | CN | disclosed |
| EP-2225174-A2 | SEPARATION OF NANOSTRUCTURES | Massachusetts Institute of Technology (US) | 2010-09-08 | — | — | EP | disclosed |
| WO-2009070240-A2 | SEPARATION OF NANOSTRUCTURES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-06-04 | — | — | WO | disclosed |