Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7849452 | 0.80 | HDAC4 (0.47) | HDAC4HDAC2HDAC8ALDH1A1HPGD | |
| SCHEMBL1006801 | 0.80 | HDAC4 (0.62) | HDAC4HDAC2HDAC8ALDH1A1HPGD | |
| SCHEMBL7839786 | 0.76 | ALDH1A1 (0.41) | HDAC4HDAC2HDAC8ALDH1A1HPGD | |
| SCHEMBL26239181 | 0.75 | HDAC4 (0.53) | HDAC4HDAC2HDAC8ALDH1A1HPGD | |
| SCHEMBL22926647 | 0.75 | HDAC4 (0.53) | HDAC4HDAC2HDAC8ALDH1A1HPGD | |
| SCHEMBL199109 | 0.75 | HDAC4 (0.53) | HDAC4HDAC2HDAC8ALDH1A1HPGD | |
| SCHEMBL25819608 | 0.75 | HDAC4 (0.53) | HDAC4HDAC2HDAC8ALDH1A1HPGD | |
| SCHEMBL7778471 | 0.74 | HDAC4 (0.56) | HDAC4HDAC2HDAC8ALDH1A1HPGD | |
| SCHEMBL198138 | 0.74 | HDAC4 (0.56) | HDAC4HDAC2HDAC8ALDH1A1HPGD | |
| SCHEMBL2092611 | 0.72 | HDAC4 (0.55) | HDAC4HDAC2HDAC8ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0953564-B1 | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS CO LTD (JP) | 2001-06-13 | — | — | EP | disclosed |
| EP-0854135-B1 | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS CO LTD (JP) | 2000-02-02 | — | — | EP | disclosed |
| US-5998652-A | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1999-12-07 | — | — | US | disclosed |
| EP-0953564-A1 | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1999-11-03 | — | — | EP | disclosed |
| EP-0854135-A2 | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1998-07-22 | — | — | EP | disclosed |