Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL598140 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TSHRCYP2C9GAAUSP2 | |
| SCHEMBL4445211 | 0.77 | TYR (0.41) | CYP2C9HPGDNPSR1NPC1RAB9A | |
| SCHEMBL7847962 | 0.76 | HDAC4 (0.53) | ALDH1A1TSHRGAAUSP2PKM | |
| Hydrogen Peroxide SCHEMBL11434421 | 0.76 | ALDH1A1 (0.59) | ALDH1A1TSHRCYP2C9GAAUSP2 | |
| SCHEMBL10317547 | 0.75 | CYP2C9 (0.42) | ALDH1A1TSHRCYP2C9GAAUSP2 | |
| SCHEMBL14705838 | 0.75 | ADRB2 (0.52) | ALDH1A1TSHRCYP2C9GAAUSP2 | |
| SCHEMBL10192291 | 0.75 | ADRB2 (0.52) | ALDH1A1TSHRCYP2C9GAAUSP2 | |
| SCHEMBL2632879 | 0.75 | ADRB2 (0.52) | ALDH1A1TSHRCYP2C9GAAUSP2 | |
| SCHEMBL25983785 | 0.75 | ALDH1A1 (0.44) | ALDH1A1TSHRCYP2C9GAAUSP2 | |
| SCHEMBL9339775 | 0.74 | ALDH1A1 (0.47) | ALDH1A1TSHRCYP2C9GAAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0953564-B1 | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS CO LTD (JP) | 2001-06-13 | — | — | EP | disclosed |
| EP-0854135-B1 | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS CO LTD (JP) | 2000-02-02 | — | — | EP | disclosed |
| US-5998652-A | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1999-12-07 | — | — | US | disclosed |
| EP-0953564-A1 | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1999-11-03 | — | — | EP | disclosed |
| EP-0854135-A2 | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1998-07-22 | — | — | EP | disclosed |