Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7839983 | 0.81 | DYRK1A (0.49) | CYP1A2MEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL7848264 | 0.72 | ALDH1A1 (0.72) | ALDH1A1KDM4ECYP1A2MEN1KMT2A | |
| SCHEMBL21440929 | 0.71 | TSHR (0.33) | MAPK1 | |
| SCHEMBL7840041 | 0.69 | ALDH1A1 (0.57) | ALDH1A1KDM4ECYP1A2MEN1KMT2A | |
| SCHEMBL24827704 | 0.69 | MAPT (0.61) | ALDH1A1KDM4ECYP1A2MEN1KMT2A | |
| SCHEMBL7848714 | 0.68 | MAOA (0.39) | KDM4EMEN1KMT2AMAPTNPC1 | |
| SCHEMBL28266343 | 0.64 | MAPT (0.61) | ALDH1A1CYP1A2MEN1KMT2AHTT | |
| SCHEMBL31373106 | 0.64 | AKR1C3 (0.62) | ALDH1A1CYP1A2MEN1KMT2AHTT | |
| SCHEMBL28266341 | 0.64 | MAPT (0.61) | ALDH1A1CYP1A2MEN1KMT2AHTT | |
| SCHEMBL7839741 | 0.64 | MEN1 (0.38) | ALDH1A1KDM4ECYP1A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754445-B1 | Photostable cosmetic light screening compositions | HOFFMANN LA ROCHE (CH) | 2001-10-24 | — | — | EP | claimed |
| US-5840282-A | SUNSCREEN AGENTS; BENZYLIDENE-TYPE STABILIZER | GIVAUDAN-ROURE (INTERNATIONAL) SA (CH) | 1998-11-24 | — | — | US | claimed |