Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7840041 | 0.90 | ALDH1A1 (0.57) | ALDH1A1KDM4EMEN1KMT2AHTT | |
| SCHEMBL7848393 | 0.83 | ALDH1A1 (0.75) | ALDH1A1KDM4EMEN1KMT2AHTT | |
| SCHEMBL7848955 | 0.83 | ALDH1A1 (0.75) | ALDH1A1KDM4EMEN1KMT2AHTT | |
| SCHEMBL7850504 | 0.82 | KDM4E (0.72) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL7848138 | 0.72 | ALDH1A1 (0.38) | ALDH1A1KDM4EMEN1KMT2AHTT | |
| SCHEMBL7840473 | 0.71 | KDM4E (0.57) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL7839741 | 0.69 | MEN1 (0.38) | ALDH1A1KDM4EMEN1KMT2AHTT | |
| SCHEMBL7850220 | 0.67 | NR1I2 (0.73) | ALDH1A1KDM4EMEN1KMT2AHTT | |
| SCHEMBL8479460 | 0.67 | NR1I2 (0.73) | ALDH1A1KDM4EMEN1KMT2AHTT | |
| SCHEMBL24827704 | 0.62 | MAPT (0.61) | ALDH1A1KDM4EMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754445-B1 | Photostable cosmetic light screening compositions | HOFFMANN LA ROCHE (CH) | 2001-10-24 | — | — | EP | claimed |
| EP-0754445-A2 | Photostable cosmetic light screening compositions | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1997-01-22 | — | — | EP | claimed |
| EP-0754445-B1 | Photostable cosmetic light screening compositions | HOFFMANN LA ROCHE (CH) | 2001-10-24 | — | — | EP | disclosed |
| EP-0754445-A2 | Photostable cosmetic light screening compositions | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1997-01-22 | — | — | EP | disclosed |