Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 10/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8212768 | 0.80 | NAMPT (0.84) | NAMPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL10290541 | 0.78 | NAMPT (0.84) | NAMPTL3MBTL1 | |
| SCHEMBL14960629 | 0.77 | SOST (0.54) | NAMPTCYP2C9 | |
| SCHEMBL19151069 | 0.75 | SOST (0.52) | NAMPTCYP2C9NPC1RAB9A | |
| SCHEMBL14960630 | 0.75 | SOST (0.52) | NAMPTCYP2C9 | |
| SCHEMBL19397258 | 0.74 | DGAT2 (0.64) | NAMPT | |
| SCHEMBL20379467 | 0.74 | NAMPT (0.80) | NAMPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL25587537 | 0.74 | SOST (0.51) | NAMPTCYP2C9RAB9A | |
| SCHEMBL5851814 | 0.73 | MDM2 (0.76) | NAMPTCYP2C9NPC1RAB9AL3MBTL1 | |
| SCHEMBL1514653 | 0.73 | HTT (0.62) | NAMPTCYP2C9NPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718300-B1 | Carbodiimide derivative | NISSHIN SPINNING (JP) | 2001-11-21 | — | — | EP | disclosed |
| US-5789588-A | BIOTIN DERIVATIIVES OF CARBODIIMIDE FOR NUCLEIC ACIDS AND PROTEINS | NISSHINBO INDUSTRIES, INC. (JP) | 1998-08-04 | — | — | US | disclosed |
| US-5700935-A | LABEL FOR INTRODUCING BIOTIN GROUP INTO NUCLEIC ACID | NISSHINBO INDUSTRIES, INC. (JP) | 1997-12-23 | — | — | US | disclosed |
| EP-0718300-A1 | Carbodiimide derivative | NISSHINBO INDUSTRIES, INC. (JP) | 1996-06-26 | — | — | EP | disclosed |