Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A1 | P53985 | 19/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 11/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.56 |
| ▸ | SLC16A7 | O60669 | 1/20 | 0.46 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7005454 | 0.95 | SLC16A1 (0.65) | SLC16A1CYP2C9CYP3A4SLC16A7SLC16A3 | |
| SCHEMBL7005642 | 0.86 | SLC16A1 (0.66) | SLC16A1CYP2C9CYP3A4SLC16A7SLC16A3 | |
| SCHEMBL5864658 | 0.76 | SLC16A1 (0.75) | SLC16A1CYP2C9CYP3A4SLC16A7 | |
| SCHEMBL7010063 | 0.74 | SLC16A1 (0.69) | SLC16A1CYP2C9CYP3A4SLC16A7 | |
| SCHEMBL14845838 | 0.74 | SLC16A1 (0.70) | SLC16A1CYP2C9CYP3A4SLC16A7SLC16A3 | |
| SCHEMBL7007619 | 0.73 | SLC16A1 (0.51) | SLC16A1CYP2C9CYP3A4SLC16A7 | |
| SCHEMBL10292856 | 0.72 | SLC16A1 (0.68) | SLC16A1CYP2C9CYP3A4SLC16A7SLC16A3 | |
| SCHEMBL7944970 | 0.72 | SLC16A1 (0.68) | SLC16A1CYP2C9CYP3A4SLC16A7SLC16A3 | |
| SCHEMBL10293348 | 0.70 | SLC16A1 (0.65) | SLC16A1CYP2C9CYP3A4SLC16A7SLC16A3 | |
| SCHEMBL7005447 | 0.69 | SLC16A1 (0.61) | SLC16A1CYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107973-A1 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012514-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2000-03-09 | — | — | WO | disclosed |